Results 51 to 60 of about 146,207 (265)

The Circadian Transcription Factor CLOCK Modulates Oxidative Stress Resistance via the ACHL–Relish Axis in Drosophila

open access: yesAdvanced Science, EarlyView.
This study identifies the circadian transcription factor CLOCK (CLK) as a key regulator of oxidative stress resistance in fruit flies. CLK controls immune responses by driving rhythmic transcription of an RNA‐binding protein‐Achilles (ACHL) in the fly brain, which post‐transcriptionally represses the NF‐κB homolog Relish, limiting immune activation and
Xu Liu   +7 more
wiley   +1 more source

Factors associated with access and utilization of sexual abuse emergency healthcare services among street children in Zomba, Malawi: a qualitative study

open access: yesBMC Health Services Research
Background Sexual abuse among street children is a problem that renders a burden of sexually transmitted diseases, HIV infection, and early pregnancy. Literature shows that globally 95 million children experience sexual abuse with 1 in 5 girls and 1 in 7
Susan Mphatso Kacheyo, Lot Nyirenda
doaj   +1 more source

Yes! Kissing Too… The Child Would Not Be Hurt in Any Way: Social Constructions of Child Sexual Abuse in the Ga Community in Ghana

open access: yesQualitative Sociology Review, 2019
The United Nations Convention on the Rights of the Child obligates nations to protect children from all forms of abuse including sexual. However, child sexual abuse is a complex phenomenon which is difficult to understand as a result of cultural reasons.
Ummu Markwei
doaj   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

open access: yesAdvanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr.   +20 more
wiley   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

open access: yesAdvanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan   +3 more
wiley   +1 more source

Prevention of Child Sexual Abuse: Parents’ Knowledge, Attitudes and Practices

open access: yesنشریه پرستاری ایران, 2014
Background & Aims: Sexual abuse is the most damaging type of abuse which has been increased significantly in recent decades so prevention of sexual abuse is crucial. This study aimed to determine the knowledge, attitude and practices of parents regarding 
S Khanjari   +3 more
doaj  

A Literature Survey on Potential Private User Information Leakage in Metaverse Applications

open access: yesAdvanced Intelligent Systems, EarlyView.
This survey explores potential privacy risks in the Metaverse, focusing on personal data inferred from virtual reality headsets embedded with passive brain‐computer interfaces (BCI). It reviews how age, gender, and ethnicity can be predicted using neurophysiological signals, (e.g., electroencephalogram). The survey also explores future threats from non‐
Mina Jaberi, Tiago H. Falk
wiley   +1 more source

Promoting radical healing to facilitate community capacity building among formerly incarcerated Black and Latino men with substance use disorders

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract This study reports on a qualitative thematic analysis of secondary data from group session recordings collected as part of the Community Wise Optimization Trial. Community Wise is a multilevel behavioral intervention designed to increase critical consciousness and reduce substance use among formerly incarcerated men living in predominantly ...
Richmond E. Hayes   +4 more
wiley   +1 more source

Using community‐based participatory research to contextualize Latino exposure to community violence: A mixed qualitative and spatial analysis approach

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract While the relationship between community violence exposure and maladaptive outcomes has been established, the dynamic between violence exposure and resilience factors in youth is not well understood. The current study utilizes a community‐based participatory research (CBPR) framework and employs a novel mixed‐methods approach integrating ...
Kyle C. Deane   +6 more
wiley   +1 more source

A Scoping Review on the Psychosocial Effects of Sexual Abuse on the Girl Child in Sub-Saharan Africa [PDF]

open access: yesE-Journal of Humanities, Arts and Social Sciences
Child sexual abuse has become a global phenomenon. The statistics of sexual abuse of a girl child by relatives and/or other people known to the girl child are shocking. Various factors predispose a girl child to be susceptible to sexual abuse.
Tsholofelo Keikabile   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy