Results 71 to 80 of about 420,913 (305)

Bivariate Copula Model on Fitting Correlated Time-to-Event Outcomes: Age at First Sex and Age at First Marriage Among Youth in Tanzania

Journal of Probability and Statistics
Traditionally, age at first sex (AFS) and age at first marriage (AFM) have been analysed independently. While useful for summarising risk factors for each outcome individually, these approaches offer limited insight into the interdependence between these
Jacqueline Materu, Eveline T. Konje, Ties Boerma, Mark Urassa, Milly Marston, Jim Todd   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Determinants of access to HIV testing and counselling services among female sex workers in sub-Saharan Africa: a systematic review

BMC Public Health, 2019
Background HIV testing and counselling (HTC) is an essential component for HIV prevention and a critical entry point into the HIV continuum of care and treatment.
Soori Nnko, Evodius Kuringe, Daniel Nyato, Mary Drake, Caterina Casalini, Amani Shao, Albert Komba, Stefan Baral, Mwita Wambura, John Changalucha   +9 more
doaj   +1 more source

What Works for Adolescent Reproductive Health: Lessons from Experimental Evaluations of Programs and Interventions [PDF]

, 2008
This Child Trends fact sheet reviews evaluated programs that focus on adolescent reproductive health. Among the findings: Many different types of programs have been shown to positively affect reproductive health outcomes.
Kristin Anderson Moore, Victoria Ball
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

The Adolescent Girls Empowerment Program: Lessons learned from the pilot test program [PDF]

, 2013
This document presents an evaluation of the Adolescent Girls Empowerment Program (AGEP), which is comprised of three major components: 1) safe spaces groups in which girls meet once a week over the course of two years for training on sexual and ...
Karen Austrian, Natalie Jackson Hachonda, Paul C. Hewett   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

W-DARE: a three-year program of participatory action research to improve the sexual and reproductive health of women with disabilities in the Philippines [PDF]

, 2015
BACKGROUND: In many contexts, women with disability have less access to sexual and reproductive health information, screening, prevention, and care services than women without disability.
Alexandra Devine, Carolyn Sobritchea, Cathy Vaughan, Jerome Zayas, Joy Garcia, Joy Salgado, Krissy Bisda, Liz Gill-Atkinson, Ma. Jesusa Marco, Manjula Marella, Sally Baker, Tanya Edmonds   +11 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Thirty years and beyond … celebrating and supporting our authors

Sexual and Reproductive Health Matters, 2023
Emma Pitchforth, Pete Chapman, Sarah Keogh, TK Sundari Ravindran   +3 more
doaj   +1 more source