Results 91 to 100 of about 631,691 (346)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Sexually Dimorphic Effect of Environmental Enrichment and Weaning on Stress in Piglets

Animals
Most intensive swine production systems use invasive practices that increase stress and compromise animal welfare. Apparently, the way in which animals respond to stress is sexually dimorphic.
Guadalupe Espejo-Beristain, Pedro Paredes-Ramos, Concepción Ahuja-Aguirre, Apolo Carrasco-García   +3 more
doaj   +1 more source

Sexual Dimorphism in Monoamine Metabolism in BrdU-Treated Rats Showing Behavioral Dopamine Hypersensitivity: An Animal Model of Schizophrenia [PDF]

, 2013
© 2013 Muneoka and Kuwagata , licensee InTech. This is an open access chapter distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Muneoka, Katsumasa, Kuwagata, Makiko
openaire   +3 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Neurophysiology of male sexual arousal—Behavioral perspective

Frontiers in Behavioral Neuroscience
In the presented review, we analyzed the physiology of male sexual arousal and its relation to the motivational aspects of this behavior. We highlighted the distinction between these processes based on observable physiological and behavioral parameters ...
Wiktor Bogacki-Rychlik, Katarzyna Gawęda, Michal Bialy   +2 more
doaj   +1 more source

High-resolution monitoring from birth to sexual maturity of a male reef manta ray, Mobula alfredi, held in captivity for 7 years: changes in external morphology, behavior, and steroid hormones levels

BMC Zoology, 2017
Background In this study, we report the first case of a male reef manta ray, Mobula alfredi, becoming sexually mature in captivity and present its reproductive characteristics.
Ryo Nozu, Kiyomi Murakumo, Rui Matsumoto, Yosuke Matsumoto, Nagisa Yano, Masaru Nakamura, Makio Yanagisawa, Keiichi Ueda, Keiichi Sato   +8 more
doaj   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

A time for sex: circadian regulation of mammalian sexual and reproductive function

Frontiers in Neuroscience
The circadian clock regulates physiological and biochemical processes in nearly every species. Sexual and reproductive behaviors are two processes controlled by the circadian timing system.
Sydney Aten, Oscar Ramirez-Plascencia, Chiara Blake, Chiara Blake, Gabriel Holder, Gabriel Holder, Emma Fishbein, Emma Fishbein, Adam Vieth, Adam Vieth, Arman Zarghani-Shiraz, Arman Zarghani-Shiraz, Evan Keister, Evan Keister, Shivani Howe, Shivani Howe, Ashley Appo, Ashley Appo, Beatrice Palmer, Carrie E. Mahoney   +19 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source