Results 41 to 50 of about 86,509 (257)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Sexual behaviour and risk of sexually transmitted infections in young female healthcare students in Spain [PDF]

open access: yesPeerJ, 2016
Background. Several authors have examined the risk for sexually transmitted infections (STI), but no study has yet analyzed it solely in relation with sexual behaviour in women.
Felipe Navarro-Cremades   +7 more
doaj   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

“It's Sweet Without Condom”: Understanding Risky Sexual Behaviour Among Nigerian Female University Students

open access: yesOnline Journal of Health & Allied Sciences, 2018
Background: Over a million people globally acquire sexually transmitted infections (STI) every day mainly through unprotected sexual contact. While the consequences of risky sexual behaviour are well documented, the literature on young educated women's ...
Anthony Idowu Ajayi   +3 more
doaj  

PARENT COMMUNICATION PATTERNS AND RISK SEXUAL BEHAVIOR IN LATE ADOLESCENT

open access: yesIndonesian Midwifery and Health Sciences Journal
Background: Risky sexual behaviour in adolescents can have a detrimental impact on adolescent development and health, such as exposure to sexually transmitted diseases including HIV/AIDS, unwanted pregnancy, and abortion.
Cindy Wahyu Agustina   +2 more
doaj   +1 more source

Does social connectedness influence risky sexual behaviours? finding from Ethiopian youths

open access: yesInternational Journal of Adolescence and Youth, 2018
Background: Various studies on risk sexual behaviours focus on personal factors. However, the influence of essential social factors needs a profound concern.
Simegnew Handebo   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Differentiation of sexual behaviour in pigs [PDF]

open access: yesBioscientifica Proceedings, 2020
Behaviour in pigs is sexually dimorphic as early as 1 month of age; mounting of penmates is observed more frequently for males than for females. This mounting reaches its highest frequency during the 2nd month of life and then declines to a low frequency in prepubertal pigs.
openaire   +2 more sources

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