Results 201 to 210 of about 88,631 (252)

Sexual differentiation of the brain and behavior

Best Practice and Research in Clinical Endocrinology and Metabolism, 2007
During the intrauterine period the human brain develops in the male direction via direct action of a boy's testosterone, and in the female direction through the absence of this hormone in a girl. During this time, gender identity (the feeling of being a man or a woman), sexual orientation, and other behaviors are programmed.
Dick Swaab
exaly   +3 more sources

Sexual Differentiation

Journal of endocrinological investigation, 2004
Abstract Sexual differentiation is a sequential process that begins at fertilization with the establishment of chromosomal sex, continues with the determination of gonadal sex, and culminates in the development of secondary sexual characteristics that comprise the male and female phenotypes. This basic paradigm (Fig.
A A, Sinisi, D, Pasquali, A, Notaro, A, Bellastella   +3 more
  +5 more sources

DISORDERS OF SEXUAL DIFFERENTIATION

Endocrinology and Metabolism Clinics of North America, 1998
An infant born with ambiguous genitalia requires an accurate and prompt diagnosis so that a management plan can be formulated. This article discusses the signaling cascade of genes that controls sexual differentiation. Clinical disorders involving sex reversal or ambiguous genitalia are discussed in relation to the genes regulating sexual development ...
G L, Warne, J D, Zajac
openaire   +2 more sources

Sexual determination and sexual differentiation

Critical Reviews in Plant Sciences, 1990
(1990). Sexual determination and sexual differentiation. Critical Reviews in Plant Sciences: Vol. 9, No. 4, pp. 295-316.
Raymonde Durand, Bernard Durand, Michel Jacobs   +2 more
openaire   +1 more source

Disorders of Sexual Differentiation

Surgical Pathology Clinics, 2010
The term, disorders of sexual differentiation, broadly represents a disjunction between genotype and phenotype. Phenotype in turn can refer to external or internal genital development. Disorders of sexual differentiation are determined at conception insofar as (1) the abnormal genotype is the aberrant genetic product of fertilization at the chromosomal
openaire   +5 more sources

Sexual Differentiation of the Brain

Hospital Practice, 1978
Ontogenetically the brain is female and, regardless of genetic sex, would remain so if not exposed to gonadal hormones at a critical stage in its development. Research in animals in which this exposure occurs after birth is providing evidence that the differentiation of the neural substrates that regulate pituitary activity and sexual behavior is ...
openaire   +2 more sources

Sexual Differentiation of the Human Hypothalamus

2002
Functional sex differences in reproduction, gender and sexual orientation and in the incidence of neurological and psychiatric diseases are presumed to be based on structural and functional differences in the hypothalamus and other limbic structures. Factors influencing gender, i.e., the feeling to be male or female, are prenatal hormones and compounds
Swaab, Dick F., Chung, Wilson C. J., Kruijver, Frank P. M., Hofman, Michael A., Ishunina, Tatjana A.   +4 more
openaire   +4 more sources

Sexual Differentiation of the Brain

1981
Publisher Summary This chapter discusses the sexual differentiation of the brain. In the mediobasal hypothalamus the gonadotropin-releasing hormone (GnRH) is secreted under the influence of neurotransmitters. It is transported by the hypothalamic-hypophysial portal vessels to the anterior pituitary, stimulating there the secretion of gonadotropins ...
openaire   +2 more sources

Sexual Differentiation

2011
Sexual differentiation is a sequential process that begins at fertilization with the establishment of chromosomal sex, continues with the determination of gonadal sex, and culminates in the development of secondary sexual characteristics that comprise the male and female phenotypes.
Michael J. Mcphaul, Richard J. Auchus
openaire   +2 more sources

Neurosteroids and brain sexual differentiation

Trends in Neurosciences, 2001
There is new evidence that the brain of developing songbirds can synthesize estradiol de novo. In males, this neurally derived estrogen might masculinize a connection within the neural song system. These results challenge traditional concepts about mechanisms of brain sexual differentiation and reveal a significant function for neurosteroids.
B A, Schlinger, K K, Soma, S E, London
openaire   +2 more sources