Results 101 to 110 of about 95,845 (291)

Leptin Aggravates Thoracic Aortic Dissection Through Impairment of Energy Metabolism in Nrip2+ Smooth Muscle Cells

Advanced Science, EarlyView.
Epidemiological data confirm obesity elevates thoracic aortic dissection (TAD) risk. Patient analyses implicate hyperleptinemia, where leptin binding to vascular smooth muscle cell (VSMC) receptors triggers Socs3‐mediated suppression of Stat5a transcriptional activity.
Ling Chen, Yujie Zhu, Xi Yang, JiangBin Wu, Keyuan Chen, Wuqing Huang, Lu Fang, Qi Zhang, Jie Chen, Jianing Gao, Huanhuan Cao, Meifang Wu, Zhihuang Qiu, Yuling Zhang, Yue Shen, Qiuyu Huang, Zhiyong Lin, Lemin Zheng, Liangwan Chen   +18 more
wiley   +1 more source

Self-Perception of Sexual Dysfunction of Adult Brazilian Women of Reproductive Age: A Cross-Sectional Study

Journal of Multidisciplinary Healthcare
Polianne Angella Oliveira Figueiredo,1 Tâmara Stéphanie Lucena de Medeiros Costa,2 Mateus Dantas de Azevedo Lima,2 Adriana Gomes Magalhães,2 Ingrid Fonsêca Damasceno Bezerra,3 Patricia Driusso,4 Vanessa Patrícia Soares de Sousa2 1Faculty of Health ...
Figueiredo PAO, Costa TSLDM, Lima MDDA, Magalhães AG, Bezerra IFD, Driusso P, de Sousa VPS   +6 more
doaj  

Postpartum sexual dysfunction: view on the problem [PDF]

РМЖ. Мать и дитя, 2019
A.G. Yaschuk1, I.I. Musin1, I.R. Rakhmatullina1, K.A. Kamalova2, K.N. Yaschuk1 1 Bashkir State Medical University, Ufa, Russian Federation 2 “Women’s health” Clinic, Ufa, Russian Federation Endocrine, anatomical, psychosomatic disorders during
A.G. Yaschuk, I.I. Musin, I.R. Rakhmatullina, K.A. Kamalova, K.N. Yaschuk   +4 more
doaj  

Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1

Advanced Science, EarlyView.
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo, Yuanyuan Li, Wensheng Li, Tongrui Wu, Yi Liu, Yacoubou Abdoul Razak Mahaman, Jianzhi Wang, Rong Liu, Wei Liu, Hui Shen, Xiaochuan Wang   +10 more
wiley   +1 more source

Construct and Criterion Validity of the Postmenopause Sexuality Questionnaire - PMSQ [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Objective To assess the construct and criterion validity of the Postmenopause Sexuality Questionnaire (PMSQ). Methods The present methodological questionnaire validation study included postmenopausal women.
Maria José Ferreira Lima, Marília Duarte Valim, Sebastião Freitas de Medeiros   +2 more
doaj   +2 more sources

Testosterone deficiency in the adult males [PDF]

, 2012
Testosterone deficiency leads to multiple problems but can be difficult to diagnose.
Cachia, Mario J.
core  

From autism to eating disorders and more: the role of oxytocin in neuropsychiatric disorders [PDF]

, 2016
Oxytocin (oxy) is a pituitary neuropeptide hormone synthesized from the paraventricular and supraoptic nuclei within the hypothalamus. Like other neuropeptides, oxy can modulate a wide range of neurotransmitter and neuromodulator activities. Additionally,
Di Bonaventura, Maria Vittoria Micioni, Gaetani, Silvana, Romano, Adele, Tempesta, Bianca   +3 more
core   +2 more sources

Critical Role of IL1R2‐ENO1 Interaction in Inhibiting Glycolysis‐Mediated Pyroptosis for Protection Against Lethal Sepsis

Advanced Science, EarlyView.
The authors have discovered that intracellular interleukin 1 receptor 2 (IL1R2) negatively regulates pyroptosis and inflammation by inhibiting glycolysis in sepsis. Soluble IL1R2 is released from macrophages undergoing pyroptosis. IL1R2 acts as a novel negative regulator of glycolysis by interacting with enolase 1 (ENO1), thereby inhibiting gasdermin D
Chuyi Tan, Han Ma, Jespar Chen, Gaifeng Ma, Alok Jha, Sipin Tan, Yaxi Zhu, Meidong Liu, Ke Liu, Xianzhong Xiao, Monowar Aziz, Huan Chen, Ping Wang, Huali Zhang   +13 more
wiley   +1 more source

Prevalence and factors associated with sexual dysfunction in climacteric women

O Mundo da Saúde, 2018
The present study aimed to verify the prevalence of sexual dysfunction in climacteric women and associated factors. This study had a cross-sectional and analytical design with women in the age group of 35 to 65 years, located in the Family Health ...
Marília Martins, Vanessa Adelina Casali Bandeira, Daiana Meggiolaro Gewehr, Evelise Moraes Berlez   +3 more
doaj  

An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for the conservative and nonpharmacological management of female pelvic floor dysfunction [PDF]

, 2016
There has been an increasing need for the terminology on the conservative management of female pelvic floor dysfunction to be collated in a clinically based consensus report.This Report combines the input of members and elected nominees of the ...
Abramov, Yoram, Almeida, Fernando G., Berghmans, Bary, Bo, Kari, Bortolini, Maria, Dumoulin, Chantale, Frawley, Helena C., Gomes, Mario, Haylen, Bernard T., McClurg, Doreen, Meijlink, Jane, Shelly, Elizabeth, Trabuco, Emanuel, Walker, Carolina, Wells, Amanda   +14 more
core   +3 more sources