Results 91 to 100 of about 1,317,549 (284)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Sociological exploration into sexual crime exploitation among underage vulnerable girls in Ghana

open access: yesDiscover Global Society
This qualitative study investigates the complex interplay of factors contributing to the vulnerability of underage girls to sexual exploitation in Ghana, including poverty, lack of parental care, and societal norms. Using a phenomenological approach, the
Ronald Osei Mensah   +2 more
doaj   +1 more source

The Existence of Legal Protection for Female Workers Against Sexual Exploitation Mode 'Staycation'

open access: yesReformasi Hukum
The term staycation as a connotation of sexual activity in a certain place has become increasingly popular in society, especially after the phenomenon of a viral case in the public.
Selvi Kurniawati   +2 more
doaj   +1 more source

Sexual Exploitation of Vulnerable Young People Looked After and Accommodated in Glasgow

open access: yes, 2013
The scoping study was commissioned to provide an estimate of the prevalence and risk of sexual exploitation amongst the looked after and accommodated population in Glasgow.
Murie, Sheila, Rigby, Paul
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Book review: Caring for a child who has been sexually exploited. London: Coram BAAF, 2017. ISBN: 9781910039656

open access: yesScottish Journal of Residential Child Care, 2018
Eileen Fursland's book Caring for a child that is sexually exploited is intended for those who work with, or care for young people who have been affected by, or are at risk of sexual exploitation.
Eileen Fursland
doaj   +1 more source

The reliability and validity of the Sexual Violence Risk-20 (SVR-20): An International Review [PDF]

open access: yes, 2009
This article reports on the current state of research about the most commonly used Structured Professional Judgement (SPJ) guidelines for sexual offender risk assessment, the Sexual Violence Risk-20 (SVR-20).
Hucker, Stephen J.   +3 more
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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