Results 101 to 110 of about 1,317,549 (284)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Youth nude image sharing and videochatting with online-only contacts
Computers in Human Behavior ReportsIntroduction: It is increasingly common for youths to engage in online communication involving sexual image sharing. While prior research has focused on peer sexting or adult solicitation of youths, less is known about youths’ sharing of nude images or ...
Kailey Roche +4 more
doaj +1 more source
Sexual exploitation and the State [PDF]
, 2021 "By the end of this chapter, you will understand more about:\ud • the effects of social, political and economic inequalities within the state and between the Global North and South on sexual exploitation\ud • how to explore the phenomenon of online and localised grooming with reference to technology, ‘race’, class, gender and institutional failure\ud •
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
SocietiesMainstream migration theory has often explained irregular immigration as an autonomous process driven primarily by individuals, families, or communities. However, the recruitment of undocumented labor by U.S.
Karla-Lorena Andrade-Rubio +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Sex Trafficking and Commercial Sexual Exploitation of Children within the Context of Globalisation
Bulletin of the Transilvania University of Braşov: Series VII: Social Sciences, LawThe issue of sex trafficking and of commercial sexual exploitation of children is not a new one, it represents a serious concern at international level, considering the enhancement of this phenomenon.
Carmina Tolbaru
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source