Results 201 to 210 of about 64,387 (299)

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Effects of Nutritional Status During Sexual Maturation and Resource Availability on the Resource Allocation of Females in Burying Beetles. [PDF]

Ecol Evol
Wang W, Zhou G, Zhang W, Tian K, Yao L.
europepmc   +1 more source

UPLC-QTOF/MS Metabolomics and Biochemical Assays Reveal Changes in Hepatic Nutrition and Energy Metabolism during Sexual Maturation in Female Rainbow Trout (Oncorhynchus mykiss). [PDF]

Biology (Basel), 2022
Ding L, Liu Y, Kang M, Wei X, Geng C, Liu W, Han L, Yuan F, Wang P, Wang B, Sun Y.   +10 more
europepmc   +1 more source

Cold Atmospheric Plasma‐Activated Decellularized Extracellular Matrix Gel as a Tumor‐Infiltrating Immunoactivation Platform for Post‐Surgical Cancer Immunotherapy

Advanced Materials, EarlyView.
An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang, Mo Chen, Yueyang Deng, Tianqin Ning, Tianwen Luo, Guojun Chen   +5 more
wiley   +1 more source

The Transcriptome Characterization of the Hypothalamus and the Identification of Key Genes during Sexual Maturation in Goats. [PDF]

Int J Mol Sci
Li Q, Chao T, Wang Y, Xuan R, Guo Y, He P, Zhang L, Wang J.   +7 more
europepmc   +1 more source

The Role of Fetal, Infant, and Childhood Nutrition in the Timing of Sexual Maturation. [PDF]

Nutrients, 2021
Calcaterra V, Cena H, Regalbuto C, Vinci F, Porri D, Verduci E, Chiara M, Zuccotti GV.   +7 more
europepmc   +1 more source

Hierarchical Structure and Fabrication of Functionally Graded Biointerfaces in the Mussel Byssus

Advanced Materials Interfaces, EarlyView.
The byssus is a fibrous protein‐based holdfast consisting of mechanically distinct interfaces, which mussels use to anchor their soft living tissue to hard seashore surfaces. Here, multiscale methodologies were used to elucidate the compositional and structural features underlying these functionally graded interfaces and how they are fabricated through
Lucia Youssef, Jenaes Sivasundarampillai, Sydney Mikulin, Franziska Jehle, Matthew J. Harrington   +4 more
wiley   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Metabolomic and Transcriptomic Analyses Reveal the Potential Mechanisms of Dynamic Ovarian Development in Goats during Sexual Maturation. [PDF]

Int J Mol Sci
Wang Y, Chao T, Li Q, He P, Zhang L, Wang J.   +5 more
europepmc   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source