Results 291 to 300 of about 190,186 (350)

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

open access: yesAdvanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun   +5 more
wiley   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

open access: yesAdvanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen   +8 more
wiley   +1 more source

Thermally Degradable Biocompatible Hydrogel as Transient Encapsulation Coating for Implantable Sensors

open access: yesAdvanced Science, EarlyView.
A biocompatible hydrogel coating with tissue‐like mechanics and reversible dissolution triggered by a mild, physiologically compatible temperature drop (≈37°C → ≈25°C) was developed for the transient encapsulation of implantable devices. The physically crosslinked methylcellulose, polyethylene glycol and polyacrilic acid (MC/PEG/PAA) hydrogel ...
Francesca Persano   +14 more
wiley   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

open access: yesAdvanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen   +11 more
wiley   +1 more source
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Sexual Maturity in Drosophila

Nature, 1959
D. J. MERRELL1 says in regard to the fertility of matings of Drosophila when employing males less than 24 hr. old and males aged for seven days: “The imaged flies were left together in the creamers for periods ranging from 18 to 72 hours; the aged flies were separated after 2 to 7 hours, the variation in time being due to differences in the length of ...
openaire   +2 more sources

Sexual Maturation in Thai Boys

Journal of Pediatric Endocrinology and Metabolism, 2010
A worldwide secular trend towards earlier onset of puberty in girls has been noted during recent years. However, the data on sexual maturation of boys are relatively scarce and normative data of sexual maturation in Thai boys are still lacking.To determine the age of secondary sexual maturation in normal Thai boys.Three hundred healthy urban boys aged ...
P, Mahachoklertwattana   +5 more
openaire   +2 more sources

Sexual Maturation in the Bull

Reproduction in Domestic Animals, 2008
ContentsIn this review, we describe the process of sexual maturation in the bull calf. The testes of the bull grow relatively slowly until approximately 25 weeks of age and then a rapid phase of growth occurs until puberty, at 37–50 weeks of age. During the early postnatal phase of slower growth of the testis pre‐spermatogonia and some spermatogonia ...
N, Rawlings   +3 more
openaire   +2 more sources

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