Results 81 to 90 of about 462,969 (291)

Initial experimental evidence that the ability to choose between items alters attraction to familiar versus novel persons in different ways for men and women [PDF]

, 2019
Nonhuman species may respond to novel mates with increased sexual motivation (‘The Coolidge Effect1). In humans, novel technological advances, such as online dating platforms, are thought to result in ‘Choice Overload’2.
Ritchie, Kay L., Sculley, Jordan, Watkins, Christopher D.   +2 more
core  

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

A Motivação Sexual dos Adolescentes: Influência dos Fatores Sociodemográficos [PDF]

, 2014
Resumo Enquadramento: A sexualidade, presente ao longo da vida, na adolescência adquire novos contornos. O início da atividade sexual pode ser considerado um dos momentos com maior impacto na vida do adolescente, tornando-se, assim, importante ...
Aparício, Graça, Duarte, João, Nelas, Paula, Oliveira, Vera   +3 more
core  

The Applicability of Behaviour Change in Intervention Programmes Targeted at Ending Female Genital Mutilation in the EU:Integrating Social Cognitive and Community Level Approaches [PDF]

, 2013
With increased migration, female genital mutilation (FGM) also referred to as female circumcision or female genital cutting is no longer restricted to Africa, the Middle East, and Asia.
Barrett, Hazel, Beecham, David, Brown, Katherine   +2 more
core   +3 more sources

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Phenotyping the males of mouse and rat strains with genetically defined behavioral disturbances in a model of sexual activation

Вавиловский журнал генетики и селекции, 2015
Sexual behavior is one of the biologically highly relevant types of behavior. Sexual arousal, or an initial stage of sexual behavior, is of particular interest since it triggers all the following events but still remains the least known element of this ...
M. A. Tikhonova, T. G. Amstislavskaya
doaj   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

The clinical effectiveness of individual behaviour change interventions to reduce risky sexual behaviour after a negative human immunodeficiency virus test in men who have sex with men: systematic and realist reviews and intervention development [PDF]

, 2017
Background: Men who have sex with men (MSM) experience significant inequalities in health and well-being. They are the group in the UK at the highest risk of acquiring a human immunodeficiency virus (HIV) infection.
Abraham, Aghaizu, Ajzen, Albarracín, Angus, Bailey, Bandura, Bartholomew, Becker, Bedoya, Berg, Berg, Berg, Blas, Borrelli, Borrelli, Bourne, Bourne, Bourne, Bowen, Bowen, Brady, British Association for Sexual Health & HIV, Brown, Bull, Cane, Carey, Carpenter, Carrico, Centers for Disease Control and Prevention, Chesney, Chiasson, Christensen, ClincalTrials.gov, ClincalTrials.gov, ClincalTrials.gov, Clutterbuck, Coffin, Cohen, Coia, Colfax, Conner, Craig, Crepaz, Crepaz, Das, Davidovich, Davidovich, DerSimonian, Desai, Dilley, Dilley, Dilley, Dilley, Dixon-Woods, Duan, Eaton, Eaton, Eaton, Elford, Ellis, European Centre for Disease Prevention and Control, Fisher, Fisher, Fletcher, Flowers, Flowers, Flowers, Flowers, Flowers, Forney, Frasca, French, Gardner, Gilbart, Glanz, Gold, Goodwin, Grantome, Gray, Guo, Hao, Health Protection Scotland, Herbst, Hidalgo, Higa, Higgins, Hightow-Weidman, Hightow-Weidman, Hirshfield, Hoaglin, Hosek, Hosek, Hosek, Huan, Hughes, Imrie, Janis, Jansen, Janz, Jbilou, Johnson, Johnson, Johnson, Johnson, Johnson, Jones, Kalichman, Kasatpibal, Kayser, Khosropour, Knussen, Ko, Koblin, Koblin, Landovitz, Lau, Lau, Lawson, Lorimer, Lu, Lucas, Macdonald, Malek, May, May, McKee, Melendez-Torres, Menza, Metcalf, Metcalf, Metsch, Michie, Michie, Michie, Michie, Michie, Mikolajczak, Mikolajczak, Mikolajczak, Miller, Mimiaga, Miranda, Moher, Morgenstern, Morgenstern, Murray, Mustanski, Mustanski, Nakagawa, Nakagawa, National Institute for Health and Care Excellence, National Institute for Health and Care Excellence, National Institute for Health and Care Excellence, Neumann, New South Wales Sexually Transmitted Infection Program Unit, NHS Healthcare Improvement Scotland, Noar, Noar, Olander, Operario, Outlaw, O’Donnell, Painter, Parsons, Pawson, Pawson, Pawson R, Phillips, Picciano, Picciano, Prestwich, Public Health England, Rashbrook, Read, Reback, Rees, Reeves, Rhodes, Rhodes, Robinson, Rosser, Rycroft-Malone, Safren, Santos, Schnall, Schwarzer, Shoptaw, Shoptaw, Shoptaw, Simms, Simms, Skarbinski, Strömdahl, Tan, Taylor, Tobin, Tracy, van Kesteren, Varney, Warner, Webb, Wilkerson, Williams, Williams, Wolfers, Wolitski, Wong, Ye, Yin, Young, Young, Zhang, Zule   +213 more
core   +3 more sources

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source