Results 161 to 170 of about 4,134 (299)

Subgroups of Adult‐Onset Diabetes: A Prospective Follow‐Up Study of Progression of Insulin Resistance and Deficiency and Association With Liver Steatosis and Fibrosis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To assess progression of insulin deficiency and resistance in diabetes, the stability of cluster‐based subgrouping, and the association between steatotic liver disease (SLD), liver fibrosis (LF), and tissue insulin resistance. Materials and Methods Participants from a regional diabetes register were studied within 3 years from diagnosis ...
Aleksi Laitinen, Annemari Käräjämäki, Aki J. Käräjämäki, Samu Kurki, Liisa Hakaste, Olof Asplund, Johan Hultman, Kaj Lahti, Mikko Lehtovirta, Emma Ahlqvist, Tiinamaija Tuomi   +10 more
wiley   +1 more source

Genomic evidence for a-α heterothallic and α-α unisexual mating and recombination in an environmental Cryptococcus deneoformans population. [PDF]

PLoS Genet
Hitchcock M, Thorn V, Samarasinghe H, Sun S, Heitman J, Xu J.   +5 more
europepmc   +1 more source

Cost‐Effectiveness of Pharmacologic Therapies for Metabolic Dysfunction–Associated Steatohepatitis With Significant Fibrosis in the United States

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The approval of new pharmacotherapies for metabolic dysfunction‐associated steatohepatitis (MASH) presents a critical need for value assessment. We evaluated the cost‐effectiveness of resmetirom, semaglutide and tirzepatide for U.S. adults with MASH and F2–F3 fibrosis.
Ali A. Abdeen, Turgay Ayer, Aanan Biswas, Chase J. Wehrle, Sobia N. Laique, Ali Aminian   +5 more
wiley   +1 more source

Off-Season Diet and Ecology of the Boll Weevil Influence Long-Term Malathion Susceptibility. [PDF]

Insects
Campos KL, Rolim GG, Silva RS, Soares MRS, Bastos CS, Torres JB.   +5 more
europepmc   +1 more source

Aristocratic identification in Felix’s Life of Guthlac

Early Medieval Europe, EarlyView.
Recent scholarship often sees high‐born monastics and clerics in early Christian England as part of the aristocratic class. Modern identity theories, however, suggest that social identity could be dynamic, situational, processual and discursive. In light of this concept, the present article reads Felix’s Life of Guthlac as a text that constructs an ...
Lek Hang Chan
wiley   +1 more source

Genetic and Epigenetic Mechanisms Underlying Reversible Adaptive Responses in Fungi. [PDF]

J Fungi (Basel)
Dan L, Liu S, Qiang Z, Ye X, Zhang J.
europepmc   +1 more source

Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild traumatic brain injury

The FEBS Journal, EarlyView.
Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester, Owen Leitzel, Samantha Golf, Chelsea M. Phillips, Michael J. Zeitz, Rahul Pandit, Elizabeth Wash, Jenna V. Donohue, Elizabeth A. Istre, James W. Smyth, Samy Lamouille, Stefanie Robel   +11 more
wiley   +1 more source

Phylogenetic constraints, conservatism, and convergence shape three-dimensional variation in flower morphology of a tropical orchid radiation. [PDF]

Plant J
Artuso S, Gamisch A, Staedler YM, Schönenberger J, Comes HP.   +4 more
europepmc   +1 more source

The Master Narrative of Prioritized Parenthood: Bifurcated Identities and Doxastic Damage in the Postpandemic Workplace

Gender, Work &Organization, EarlyView.
ABSTRACT Women's work experiences during COVID‐19 illuminated or exacerbated existing organizational divides between mothers and childfree employees as presumptions related to time management, differences in access to resources, and implicit organizational expectations became more visible.
Cristin A. Compton, Jaclyn K. Brandhorst, Keira Solon   +2 more
wiley   +1 more source

RNAi epimutations conferring antifungal drug resistance are inheritable. [PDF]

Nat Commun
Pérez-Arques C, Navarro-Mendoza MI, Xu Z, Walther G, Heitman J.   +4 more
europepmc   +1 more source