Results 211 to 220 of about 896,121 (306)

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar   +15 more
wiley   +1 more source

Stac2 genetic deletion alters mouse chromaffin cells’ CaV channel composition, increases membrane excitability and reduces vesicle exocytosis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Stac2 adaptor protein is expressed in neurons and endocrine cells. Using a global Stac2 knockout mouse model here we investigated the role of endogenous Stac2 in adrenal gland mouse chromaffin cell (MCC) excitability and catecholamine vesicle exocytosis.
Stefanie M. Geisler   +6 more
wiley   +1 more source

Concept Creep and the Mental Health Crisis

open access: yesSocial Issues and Policy Review, Volume 20, Issue 1, December 2026.
ABSTRACT Many explanations have been offered for the rising prevalence of mental health complaints. I present an account that attributes some of this increase to historical changes in mental health‐related concepts that are propelled by broad cultural trends.
Nick Haslam
wiley   +1 more source

Viewing Time Behavior in a Diverse Sample of 320 Pedohebephilic and Teleiophilic Men Who Have Committed Child Sexual Offense and Who Have Not. [PDF]

open access: yesArch Sex Behav
Hoffmann C   +10 more
europepmc   +1 more source

Epigenetic Markers of Cell Division and Ageing in Relation to Breast Cancer Survival

open access: yesInternational Journal of Cancer, Volume 159, Issue 10, Page 2452-2462, 15 November 2026.
ABSTRACT Breast cancer remains a major challenge to public health. Biomarkers may be useful to improve prediction of breast cancer survival. Several epigenetic markers of cell division and ageing based on DNA methylation have been proposed. In this study, we measured these epigenetic markers in breast tumours and assessed their prognostic value.
Luca Li   +10 more
wiley   +1 more source

Changing organizational culture in community sport: a systematic review. [PDF]

open access: yesFront Sports Act Living
Woodforde J   +5 more
europepmc   +1 more source

HOPE Kids 2: Phase 3, Randomized Trial of Voxelotor in Children With SCD and Conditional Cerebral Blood Flow Velocities

open access: yesAmerican Journal of Hematology, Volume 101, Issue 11, Page 2799-2811, November 2026.
ABSTRACT Children with SCD have elevated stroke risk, correlated with cerebral blood flow velocity (CBFV). HOPE Kids 2 was a phase 3, multicenter, double‐blind, placebo‐controlled trial evaluating the effect of voxelotor on CBFV. Participants aged 2 to < 15 years with SCD (HbSS/HbSβ0) and conditional CBFV (170 to < 200 cm/s) were randomized 1:1 to ...
Halima Bello‐Manga   +58 more
wiley   +1 more source

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