Results 61 to 70 of about 81,925 (304)

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Satisfaction-adaptation principles in sexual desire: exploring gender differences across the lifespan

, 2014
Sexual desire may change according to two principles: the satisfaction principle (high sexual opportunity/frequency decreases sexual desire) and the adaptation principle (high sexual opportunity/frequency increases sexual desire). We explore the workings
Baumeister, Roy F., Sedikides, Constantine, Sedikides, C., Gebauer, Jochen E., Baumeister, R.F., Neberich, W., Neberich, Wiebke, Gebauer, J.E.   +7 more
core   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

The sexual excitation/sexual inhibition inventory for women: psychometric properties

, 2006
This is a post-print version of the article. The official published version can be found at the link below.This article reports on the development of a new questionnaire designed to assess the propensity for sexual excitation and sexual inhibition in ...
Milhausen, RR, Sanders, Stephanie A., Milhausen, Robin R., Sanders, SA, Graham, CA, Graham, Cynthia A.   +5 more
core   +1 more source

Body image and marital satisfaction: Evidence for the mediating role of sexual frequency and sexual satisfaction. [PDF]

Journal of Family Psychology, 2010
How does women's body image shape their interpersonal relationships? Based on recent theories of risk regulation and empirical evidence that sex is an emotionally risky behavior, we predicted that women's body image would predict increased sexual frequency and thus increased sexual and marital satisfaction for both members of established relationships.
Andrea L, Meltzer, James K, McNulty
openaire   +2 more sources

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

HP-08-004 Factors involved in sexual function and sexual satisfaction in patients undergoing inflatable penile prosthesis implantation

, 2017
Objective: Penile prosthesis implantation (PPI) represents the gold standard treatment for erectile dysfunction when conservative approaches (oral PDE-5 inhibitors, transurethral suppositories or prostaglandin injections) fail.
F. Tripodi, Silvaggi, M., Tripodi, F., SIMONELLI, Chiara, P. Grande, DI PIERRO, GIOVANNI BATTISTA, F. Nimbi, LEMMA, ANDREA, GRANDE, PIETRO, ANTONINI, GABRIELE, A. Lemma, A. Fabrizi, G. Di Pierro, FABRIZI, ADELE, M. Silvaggi, NIMBI, FILIPPO MARIA, C. Cristini, R. Rossi, C. Simonelli, CRISTINI, Cristiano, ROSSI, ROBERTA, G. Antonini   +21 more
core   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Components Of Sexual Satisfaction As Identified By Emerging Adults

, 2023
Background and Objectives: Presented are the preliminary findings of an examination of sexual satisfaction as identified by college students. The goal of the present research is to examine how sexually active, heterosexual emerging adults rated the ...
Osborn, Ramsey McKenna, NC DOCKS at East Carolina University   +1 more
core  

Impact of methamphetamine and opium use in sexual satisfaction and body image in married substance and non-substance user men

Social Determinants of Health, 2015
Background: sexual satisfaction is a vital component in marital satisfaction and life quality. The appraisal has influence sexual satisfaction. The previous study shows that people use methamphetamine and opium for enhancing sexual functioning.Objectives:
Anahita Khodabakhshi Koolaee, Ali Sarvestani, Ladan Mansour, Hassan Habibi, Masoumeh Rahmatizadeh   +4 more
doaj   +3 more sources