Results 81 to 90 of about 437,569 (306)

Development of the Occupational Performance Inventory of Sexuality and Intimacy (OPISI): Phase One [PDF]

, 2020
Background: The occupational therapy profession needs a framework to guide understanding of the occupational nature of sexuality and intimacy, assessment, intervention design, and measurement of outcomes.
Christy, Davis, Faulkner, Tori, Hess, Pamela, Kaizer, Kandyse, LeMond, Kelsey, Otte, Kasey, Walker, Beth Ann   +6 more
core   +2 more sources

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

Satisfação com a vida sexual em pessoas idosas [PDF]

, 2012
Este estudio examinó la satisfacción de la vida sexual entre las personas mayores. Los objetivos fueron dos, comprobar si existían diferencias en la satisfacción con la vida sexual de acuerdo a las características sociodemográficas en su relación con el ...
Neto, Félix, Pinto, Maria da Conceição   +1 more
core   +1 more source

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

Advanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu, Xuedi Zhang, Ying Zhou, Jie Zheng, Angyang Sun, Kailong Zhuang, Weiwei Bao, Guanjun Gao   +7 more
wiley   +1 more source

Sexual function and quality of life of low-risk pregnant women [PDF]

, 2012
PURPOSE: To evaluate, in healthy women in the second trimester of pregnancy, a possible association between sexual function and quality of life, and between sexual function and sexual satisfaction. METHODS: This cross-sectional study involved 51 pregnant
Abdo, Carmita Helena Najjar, Ferreira, Denise Queiroz, Mariani Neto, Corintio, Nakamura, Mary Uchiyama, Ribeiro, Meireluci Costa, Santana, Tânia das Graças Mauadie, Souza, Eduardo de   +6 more
core   +3 more sources

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Attachment-related anxiety is associated with poor genital satisfaction and sexual problems in women

BMC Women's Health, 2020
Background Genital satisfaction has been found to influence women’s sexual experience. We tested the Relational Bodily Experiences Theory (RBET) that predicts associations between women’s genital satisfaction, attachment models, and sexual desire.
Nikola Komlenac, Margarethe Hochleitner
doaj   +1 more source

Sexual satisfaction across cultures, genders, languages, and sexual orientations: Validation of the Global Measure of Sexual Satisfaction.

Psychology of Sexual Orientation and Gender Diversity
Sexual satisfaction can be important for overall well-being and has been described as a sexual right. Individual and cultural factors, such as gender identity and sexual orientation, may influence theways in which individuals describe, share, or experience their sexuality.
Marie-Michèle Paquette, Sophie Bergeron, Noémie Bigras, Mónika Koós, Léna Nagy, Shane W. Kraus, Zsolt Demetrovics, Marc N. Potenza, Rafael Ballester-Arnal, Dominik Batthyány, Joël Billieux, Peer Briken, Julius Burkauskas, Georgina Cárdenas-López, Joana Carvalho, Jesús Castro-Calvo, Lijun Chen, Giacomo Ciocca, Ornella Corazza, Rita I. Csako, David P. Fernandez, Elaine F. Fernandez, Hironobu Fujiwara, Johannes Fuss, Roman Gabrhelík, Ateret Gewirtz-Meydan, Biljana Gjoneska, Mateusz Gola, Joshua B. Grubbs, Hashim T. Hashim, Md. Saiful Islam, Mustafa Ismail, Martha C. Jiménez-Martínez, Tanja Jurin, Ondrej Kalina, Verena Klein, András Költő, Sang-Kyu Lee, Karol Lewczuk, Chung-Ying Lin, Christine Lochner, Silvia López-Alvarado, Kateřina Lukavská, Percy Mayta-Tristán, Dan J. Miller, Oľga Orosová, Gábor Orosz, Hyein Chang, Kyeongwoo Park, Fernando P. Ponce, Gonzalo R. Quintana, Gabriel C. Quintero Garzola, Jano Ramos-Diaz, Kévin Rigaud, Ann Rousseau, Marco De Tubino Scanavino, Marion K. Schulmeyer, Pratap Sharan, Mami Shibata, Sheikh Shoib, Vera Sigre-Leirós, Luke Sniewski, Ognen Spasovski, Vesta Steibliene, Dan J. Stein, Carol Strong, Berk C. Ünsal, Marie-Pier Vaillancourt-Morel, Marie Claire Van Hout, Beáta Bőthe   +69 more
openaire   +1 more source

RENAL‐CHIP: Rejection Evaluation via Non‐Invasive Analysis of Circulating Podocytes With Herringbone‐Chip Isolation Platform

Advanced Science, EarlyView.
RENAL‐CHIP converts 1 mL of peripheral blood into a biopsy‐equivalent readout of renal‐allograft fate. By magnetic capture and release of donor‐derived circulating podocytes through a herringbone microfluidic chip, 84% capture, 96% release and single‐cell RNA evidence of rejection‐specific immunity are achieved.
Juan Song, Yilong Liu, Zeyuan Zheng, Ming Zhu, Yuning Zou, Pei Liu, Yue Zheng, Xiyuan Yu, Jianzhong Zheng, Chen Shao, Huimin Zhang, Chaoyong Yang   +11 more
wiley   +1 more source

Sexual satisfaction in postmenopausal women

Payesh, 2019
Objective (s): Menopause is a normal event in the women’s lives and as one of the most important issues in reproductive health has a special importance.
Hedyeh riazi, Neda Shokri, Armin Firoozi, Maliheh Nasiri, Zohreh Sheikhan   +4 more
doaj