Results 101 to 110 of about 829,398 (278)

Sexual Selection

open access: yesEuropean Journal of Women's Studies, 2004
Today the modern Darwinian theory of evolution is the unifying theory within the biological sciences. A consideration of its implications for feminism is, however, impossible without a critical evaluation of its history of male bias. The aim of this article is therefore threefold. First, to explain what sexual selection entails.
openaire   +2 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Field estimates of parentage reveal sexually antagonistic selection on body size in a population of Anolis lizards

open access: yesEcology and Evolution, 2016
Sexual dimorphism evolves when selection favors different phenotypic optima between the sexes. Such sexually antagonistic selection creates intralocus sexual conflict when traits are genetically correlated between the sexes and have sex‐specific optima ...
Mary C. Duryea   +3 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Sexual selection and hermaphroditic organisms: Testing theory

open access: yesCurrent Zoology, 2013
Sexual selection is widespread if not ubiquitous in hermaphroditic organisms. Although many phenomena that have been described as sexual selection in gonochores, (e.g. harem polygamy, multiple mating, elaborate courtship, even secondary sexual characters)
Janet L. LEONARD
doaj  

Rapid male plumage evolution drives sexual dichromatism in Ficedula flycatchers

open access: yesAvian Research
Sexual dichromatism represents a major form of phenotypic differentiation between the sexes in birds, and its evolution is likely shaped by the interplay between sexual and natural selection.
Lijun Gao   +3 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Sexual dimorphism in the South American water snake Helicops polylepis (Serpentes: Dipsadidae)

open access: yesPhyllomedusa: Journal of Herpetology, 2021
Sexual selection, fecundity selection and ecological divergence have been the main explanations proposed for the origin and maintenance of sexual dimorphism.
Isla Carol Marialva Camargo   +5 more
doaj  

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