Results 101 to 110 of about 788,788 (345)

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

Advanced Science, EarlyView.
ABSTRACT Multiple myeloma (MM) is a hematologic malignancy driven by clonal expansion of malignant plasma cells. Despite the long‐term disease control achieved with immunotherapies in some patients, treatment resistance remains a major cause of disease relapse.
Huiyao Gu, Zhenfeng Dai, Xi Huang, Enfan Zhang, Xinyuan Dai, Haoguang Chen, Wen Cao, Jinna Zhang, Yifan Hou, Haimeng Yan, Yang Yang, Li Yang, Yi Li, Wenlong Lin, Zhen Cai, Jingsong He   +15 more
wiley   +1 more source

Intimate Partner Violence and Sexual Violence in the State of Alaska: Key Results from the 2010 Alaska Victimization Survey [PDF]

, 2011
This document is a two-page summary of the key results from the 2010 Alaska Victimization Survey for Alaska statewide. The Alaska Victimization Survey, designed to establish a baseline for estimates of intimate partner and sexual violence, is modeled ...
Rosay, André B.
core  

BREAKING THE SILENCE: REPORTS OF ADOLESCENTS AND YOUNG PEOPLE ABOUT SEXUAL VIOLENCE [PDF]

, 2022
Priscila de Vasconcelos Monteiro, Maria Lúcia Duarte Pereira, Elys Oliveira Bezerra, Débora Linhares Militão Vasconcelos, Vitória Pessoa Nogueira, Beatriz Viana da Silva, Anna Jessyca Andrade Lacerda   +6 more
openalex   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

Intimate Partner Violence and Sexual Violence in the Fairbanks North Star Borough: Key Results from the 2011 Alaska Victimization Survey [PDF]

, 2011
This document is a two-page summary of the key results from the 2011 Alaska Victimization Survey for the Fairbanks North Star Borough, which was conducted from April to June 2011, with results released on October 7, 2011 in Fairbanks. Findings include:
Rosay, André B.
core   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

Hidden Violence: Preventing and Responding to Sexual Exploitation and Sexual Abuse of Adolescent Boys [PDF]

, 2012
Boys and girls experience sexual violence and sexual exploitation in gender differentiated ways. Numerous national-level surveys have found that boys experience these forms of violence at lower rates than girls do, but at rates that nevertheless merit ...
Gary Barker, Piotr Pawlak
core  

The Effect of Providing Education on Gender Knowledge through Videos on Teenagers in the Prevention of Sexual Violence

, 2022
Maryanah, Siti Masitoh, Maghfirotul Mahrid Dzikar   +2 more
openalex   +2 more sources

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Sexual violence in nightlife and positive bystander intervention in an English city

BMC Public Health
Background Nightlife environments are high risk settings for sexual violence and bystander intervention programmes are being developed in response.
Zara Quigg, Rebecca Bates, Nadia Butler, Chloe Smith, Charley Wilson, Amanda Atkinson, Mark A Bellis   +6 more
doaj   +1 more source