Results 101 to 110 of about 2,215,465 (390)

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

open access: yesAdvanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin   +11 more
wiley   +1 more source

Machine‐Learning Decomposition Identifies a Big Two Structure in Human Personality with Distinct Neurocognitive Profiles

open access: yesAdvanced Science, EarlyView.
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang   +7 more
wiley   +1 more source

Sexual violence: Raising the conversations, a literature review [PDF]

open access: yes, 2008
This literature review is intended to contribute to efforts to raise awareness and conversations around sexual violence. It is focused on men’s sexual violence against adolescent and adult women.
Oulton, Heather, Robertson, Neville
core   +1 more source

Estimating the costs of gender-based violence in the European Union [PDF]

open access: yes, 2014
The purpose of the study is to identify and recommend appropriate methodologies to measure the cost of gender-based and intimate partner violence in EU-28 Member States.
European Institute of Gender Equality (EIGE)   +2 more
core   +2 more sources

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

open access: yesAdvanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher   +15 more
wiley   +1 more source

Experiences of sexual violence among women seeking services at a family planning unit in Sweden

open access: yesUpsala Journal of Medical Sciences, 2019
Background: Experiences of sexual violence among women can lead to ill health and increase the risk of lifetime co-occurrence of violence. Identifying risk factors and victims facilitates development of effective programmes for treatment and prevention ...
Mariella Öberg   +2 more
doaj   +1 more source

Global and Regional Estimates of Violence Against Women: Prevalence and Health Effects of Intimate Partner Violence and Non-Partner Sexual Violence [PDF]

open access: yes, 2013
Violence against women is a significant public health problem, as well as a fundamental violation of women's human rights.This report, developed by the World Health Organization, the London School of Hygiene and Tropical Medicine and the South African ...
Christina Pallitto   +4 more
core  

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

[Sexual violence--sexualized violence].

open access: yesPsychiatria Danubina, 2006
The fusion of sexuality and violence is a major issue of concern and has become a central issue of social policy. That fusion can be observed in private circumstances as well as in society at large. Children and young people as well as women and men can fall victim to that phenomenon.
openaire   +1 more source

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