Results 131 to 140 of about 2,215,465 (390)

Teen Dating Violence in New Hampshire: Who Is Most at Risk? [PDF]

open access: yes, 2017
In this brief, authors Katie Edwards and Angela Neal discuss the results of a study examining how demographic characteristics such as sexual orientation, school characteristics such as the school poverty rate, and community characteristics such as the ...
Edwards, Katie, Neal, Angela
core   +1 more source

An Open‐Source Pipeline for Calcium Imaging and All‐Optical Physiology in Human Stem Cell‐Derived Neurons

open access: yesAdvanced Science, EarlyView.
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber   +12 more
wiley   +1 more source

Sexual violence in nightlife and positive bystander intervention in an English city

open access: yesBMC Public Health
Background Nightlife environments are high risk settings for sexual violence and bystander intervention programmes are being developed in response.
Zara Quigg   +6 more
doaj   +1 more source

Physical and Psychological Violence at the Workplace [PDF]

open access: yes, 2013
[Excerpt] Key findings Workplace violence is a social phenomenon of a certain magnitude. Overall, approximately 6% of European workers report having experienced some form of workplace violence, either physical or psychological, in the past 12 months ...
Eurofound
core   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

open access: yesAdvanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun   +11 more
wiley   +1 more source

Salvage: Gendered Violence in Activist Communities [PDF]

open access: yes, 2016
How to best deal with sexual violence in radical social movements is a contentious issue in the UK Left. The persistence of and inability to deal with sexual violence contradicts the core values of equality and social justice at the heart of radical ...
Downes, Julia   +2 more
core  

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

open access: yesAdvanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun   +5 more
wiley   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

open access: yesAdvanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen   +8 more
wiley   +1 more source

Beyond Silence, Towards Refusal: The Epistemic Possibilities of #MeToo [PDF]

open access: yes, 2019
There are many ways to understand the meanings of the #MeToo movement. Analyses of its significance have proliferated in popular media; some academic analyses have also recently appeared. Commentary on the philosophical and epistemic significance of the #
Miller, Sarah
core  

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

open access: yesAdvanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen   +11 more
wiley   +1 more source

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