Results 231 to 240 of about 2,105,134 (400)

XPC Deficiency Activate Cisplatin‐Mediated Autophagy in Bladder Cancer by Limiting Novel PHRF1‐Mediated Ubiquitination of the p53 Protein

open access: yesAdvanced Science, EarlyView.
This study reveals that XPC regulates autophagy signaling beyond its noncanonical DNA repair role, uncovering the XPC‐p‐ATM‐KDM4A‐PHRF1 axis as a novel mechanism for autophagy modulation under DNA damage stress. It identifies PHRF1 as a novel p53 ubiquitin ligase.
Baixiong Zhao   +10 more
wiley   +1 more source

Patterns and dynamics of conflict-related sexual violence: an insight from 54 African countries. [PDF]

open access: yesInt J Equity Health
Babatope AE   +5 more
europepmc   +1 more source

Why we need to talk about sexual violence in the military

open access: gold, 2017
Lauren Godier‐McBard   +2 more
openalex   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

open access: yesAdvanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong   +22 more
wiley   +1 more source

Exploring the Connection Between Substance Use and Mental Health in Brazilian Teens Who Have Experienced Sexual Violence. [PDF]

open access: yesInt J Psychol
Scatena A   +5 more
europepmc   +1 more source

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

open access: yesAdvanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang   +27 more
wiley   +1 more source

Sexual exploitation and violence of prostituted children

open access: gold, 2020
Bagong Suyanto   +2 more
openalex   +2 more sources

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