Results 61 to 70 of about 93,431 (321)

Reflections on Increasing the Value of Data on Sexual Violence Incidents against Children to Better Prevent and Respond to Sexual Offending in Kenya

Societies, 2022
In many countries, data collection on sexual violence incidents is not integrated into the healthcare system, which makes it difficult to establish the nature of sexual offences in this country.
Zidan Ji, Sarah Rockowitz, Heather D. Flowe, Laura M. Stevens, Wangu Kanja, Kari Davies   +5 more
doaj   +1 more source

Guarding the Guardians: Automated Analysis of Online Child Sexual Abuse [PDF]

arXiv, 2023
Online violence against children has increased globally recently, demanding urgent attention. Competent authorities manually analyze abuse complaints to comprehend crime dynamics and identify patterns. However, the manual analysis of these complaints presents a challenge because it exposes analysts to harmful content during the review process.
arxiv  

Sexual violence in comics [PDF]

Journal of Graphic Novels and Comics, 2017
This is the first of two special issues of the Journal of Graphic Novels and Comics dedicated to the exploration of the representation of sexual violence in the medium of comics.
Mihaela Precup, Rebecca Scherr
openaire   +2 more sources

TRAF3IP3 Induces ER Stress‐Mediated Apoptosis with Protective Autophagy to Inhibit Lung Adenocarcinoma Proliferation

Advanced Science, EarlyView.
Schematic diagram of the working model of TRAF3IP3 in the coordination of ER stress and autophagy related apoptosis in lung cancer cells. Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. While upregulated in most malignancies and critical for immune regulation.
Guang Zhao, Jun Qi, Fang Li, Haotian Ma, Rui Wang, Xiuyi Yu, Yufei Wang, Sida Qin, Jie Wu, Chen Huang, Hong Ren, Boxiang Zhang   +11 more
wiley   +1 more source

Co-creating a global shared research agenda on violence against women in low- and middle-income countries

Health Research Policy and Systems
Background Despite a large growth in evidence on violence against women (VAW) over the last 25 years, VAW persists, as do gaps in the field’s knowledge of how to prevent and respond to it.
Julienne Corboz, Elizabeth Dartnall, Chay Brown, Emma Fulu, Sarah Gordon, Mark Tomlinson   +5 more
doaj   +1 more source

Caspase‐6/Gasdermin C‐Mediated Tumor Cell Pyroptosis Promotes Colorectal Cancer Progression Through CXCL2‐Dependent Recruitment of Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
Hypoxic and low‐glucose conditions in tumor tissues trigger colorectal tumor cell pyroptosis via sequential activation of the Caspase‐1/Caspase‐6/GSDMC axis. High mobility group box 1 (HMGB1), released from GSDMC‐mediated pyroptotic tumor cells, upregulates CXCL2 expression in adjacent tumor cells, thereby recruiting myeloid‐derived suppressor cells ...
Hanchao Gao, Yikun Yao, Weilong Li, Zigan Xu, Wenjun Hu, Kewang Luo, Peishan Chen, Wanjing Shang, Shaodong Luan, Guojun Shi, Mengtao Cao, Pengfei Chen   +11 more
wiley   +1 more source

A rare homozygous missense GDF2 (BMP9) mutation causing PAH in siblings: Does BMP10 status contribute?

American Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 228-233, January 2023., 2023
Abstract Pulmonary arterial hypertension (PAH) is a disease characterized by pathological remodeling of the pulmonary vasculature causing elevated pulmonary artery pressures and ultimately, right ventricular failure from chronic pressure overload. Heterozygous pathogenic GDF2 (encoding bone morphogenetic protein 9 (BMP9)) variants account for some (>1%)
Paul Upton, Susan Richards, Angela Bates, Karen Y. Niederhoffer, Nicholas W. Morrell, Susan Christian   +5 more
wiley   +1 more source

Building knowledge to improve access to inclusive and equitable care for trans and gender-diverse survivors of sexual assault and intimate partner violence: a qualitative research protocol

BMJ Open
Introduction Intimate partner violence (IPV) and sexual assault are pervasive public health and human rights concerns that disproportionately impact trans and gender-diverse (TGD) individuals.
Alexa R Yakubovich, Janice Du Mont, Sarah Daisy Kosa, Sheila Macdonald, Danielle Toccalino, C Emma Kelly, Sav Jonsa, Adam Davies   +7 more
doaj   +1 more source

Towards Automated Sexual Violence Report Tracking [PDF]

arXiv, 2019
Tracking sexual violence is a challenging task. In this paper, we present a supervised learning-based automated sexual violence report tracking model that is more scalable, and reliable than its crowdsource based counterparts. We define the sexual violence report tracking problem by considering victim, perpetrator contexts and the nature of the ...
arxiv  

Loss of Golga7 Suppresses Oncogenic Nras‐Driven Leukemogenesis without Detectable Toxicity in Adult Mice

Advanced Science, EarlyView.
NRAS mutations are widespread in hematologic malignancies. Our study shows that GOLGA7 serves as a safe and effective therapeutic target for NRAS‐driven leukemia. Loss of Golga7 in adult mice effectively suppresses NrasG12D‐driven myeloproliferative neoplasm by disrupting its PM localization and impairing subsequent MAPK signaling, without affecting ...
Bo Jiao, Lei Yan, Rui Zhang, Wei Huang, Xinru Wang, Chenxuan Liu, Peihong Wang, Pengfei Xu, Jinzeng Wang, Zhou Fang, Donghe Li, Zhizhou Xia, Jiaoyang Li, Shiyu Ji, Qianqian Zhang, Min Wu, Shengyue Wang, Ping Liu, Ruibao Ren   +18 more
wiley   +1 more source