Results 231 to 240 of about 236,714 (368)

Nuclear‐Localized BCKDK Facilitates Homologous Recombination Repair to Support Breast Cancer Progression and Therapy Resistance

Advanced Science, EarlyView.
Under DNA damage, tumor cells rely on efficient DNA repair for survival and therapy resistance. This study has demonstrated that BCKDK localizes to breast cancer cell nuclei, where it binds to and phosphorylates RNF8, thereby blocking ubiquitin‐mediated degradation of RAD51 and enhancing HRR. A selective BCKDK inhibitor synergizes with clinical agents,
Haiying Liu, Jiaqian Feng, Tingting Pan, Pinggen Zhang, Ling Ye, Zetan Jiang, Zilong Zhou, Qiankun Mao, Jian Li, Xinyi Yang, Ping Gao, De Huang, Huafeng Zhang   +12 more
wiley   +1 more source

Client Perspectives on Addressing Intimacy, Romance and Sexuality in Early Psychosis Intervention Programmes. [PDF]

Early Interv Psychiatry
Woolridge SM, Wilkinson E, Hau I, Stewart CA, Edirisinghe S, Aidelbaum R, Best MW, Bowie CR.   +7 more
europepmc   +1 more source

PATTERNS OF SEXUALITY, ASEXUAL REPRODUCTION AND RECRUITMENT IN SOME SUBTIDAL MARINE DEMOSPONGIAE

, 1980
Avril L. Ayling
openalex   +2 more sources

Sexuality education: emerging trends in evidence and practice.

Journal of Adolescent Health, 2015
N. Haberland, D. Rogow
semanticscholar   +1 more source

MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue

Advanced Science, EarlyView.
This study demonstrates that MTCH2 acts as an evolutionarily conserved regulator of energy homeostasis across Drosophila, rodents, and humans. Adipose‐specific MTCH2 ablation enhances brown/beige adipose thermogenesis through Bcl‐2‐dependent autophagy, promoting energy expenditure and counteracting obesity‐associated metabolic disorders. These findings
Xin‐Yuan Zhao, Ben‐Chi Zhao, Hui‐Lin Li, Ying Liu, Bei Wang, An‐Qi Li, Tian‐Shu Zeng, Hannah Xiaoyan Hui, Jia Sun, Domagoj Cikes, Nele Gheldof, Jorg Hager, Jian‐Xun Mi, D. Ross Laybutt, Yin‐Yue Deng, Yan‐Chuan Shi, G. Gregory Neely, Qiao‐Ping Wang   +17 more
wiley   +1 more source

Why the European Journal of Public Health and EUPHA are opposing President Trump's attack on the language of diversity. [PDF]

Eur J Public Health
Allebeck P, Albreht T, Marchandise C, McKee M.   +3 more
europepmc   +1 more source

Degrees of sexuality in sexual plants of guineagrass by the simplified embryo sac analysis.

, 1983
Kousuke Nakajima, Noboru Mochizuki
openalex   +2 more sources

Handbook of Sexuality-Related Measures [PDF]

, 1999
Gregory F. Sanders, Clive M. Davis, William L. Yarber, Robert Bauserman, George E. Schreer, Sandra L. Davis   +5 more
openalex   +1 more source

A Rapid Cortical Learning Process Supporting Students’ Knowledge Construction During Real Classroom Teaching

Advanced Science, EarlyView.
There is growing interest in understanding how classroom teaching works, but previous theories and studies leave a gap in the neurocognitive mechanisms involved in real classroom teaching. Here we show that during real classroom teaching, students' middle frontal cortex serves as a hub of a rapid cortical learning process, supporting their knowledge ...
Xiaodan Feng, Xinran Xu, Zhaonan Meng, Jiahao Jiang, Miao Pei, Yonghe Zheng, Chunming Lu   +6 more
wiley   +1 more source

A systematic review of sexual health, knowledge, and behavior in Autism Spectrum Disorder. [PDF]

BMC Psychiatry
Motamed M, Hajikarim-Hamedani A, Fakhrian A, Alaghband-Rad J.   +3 more
europepmc   +1 more source