Results 101 to 110 of about 16,419,233 (281)

Gapless Complete Genome and Multi‐Omics Illuminate Immune Adaptation and Host‐Virus Interactions in a Coronavirus Reservoir

Advanced Science, EarlyView.
We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang, Sheng Zhang, Linxia Ouyang, Xin Du, Xin Huang, Zhilin Wang, Huixian Xie, Jiale Tang, Liyi Lou, Wenqing Ling, Weihao Wang, Jiang Zhou, Zhen Liu, Yibo Hu, Fuwen Wei, Guangping Huang   +15 more
wiley   +1 more source

Identifying subgroups of Chinese men who have sex with men based on sexual behavior and drug use patterns using a clustering analysis approach

BMC Public Health
Introduction Sexualized drug use (SDU) refers to using drugs before and during sex to enhance experiences, increasing high-risk behaviors, such as condomless sex, multiple sexual partners, and participation in group sex, among men who have sex with men ...
Bingyang She, Jiajun Sun, Fang Lu, Siqi Lin, Yi Liu, Gaixia Li, Yawu Hu, Weiming Tang, Rayner Tan, Jason Ong, Shu Su, Lei Zhang   +11 more
doaj   +1 more source

Dealing with drug use.

, 2017
Drug policy is complex, but it is entirely possible to implement a policy that would better manage drug use in Ireland. Tony Duffin, CEO of the Ana Liffey Drug Project gives his perspective on what’s happening now and next.....
Duffin, Tony
core  

Lithium‐Doped Hydroxyapatite Nanowires Rejuvenate Senescent Macrophages Via the Lysosome‐Dependent Ferroptosis Axis to Promote Aged Bone Regeneration

Advanced Science, EarlyView.
Li‐nHAP+GelMA promotes mandibular bone regeneration in aged mice by remodeling the senescent immune microenvironment. Local delivery of Li‐nHAP restores lysosomal homeostasis in senescent macrophages, reduces intracellular labile Fe2+ accumulation, ROS production, and lipid peroxidation, thereby suppressing macrophage ferroptosis and senescence ...
Baixi Chen, Ziduan Ding, Ruomei Li, Cheng Zhu, Zhiyu Zhu, Zitong Yang, Luyao Qu, Jin Hao, Lunguo Xia, Bing Fang, Lu Liu   +10 more
wiley   +1 more source

Healthcare Access Among Individuals Who Practice Chemsex in Brazil: A Scoping Review Protocol

Nursing Reports
Background: Chemsex, the intentional use of psychoactive substances to enhance sexual experiences, is an emerging public health issue in Brazil, associated with increased risks of sexually transmitted infections and complex psychosocial vulnerabilities ...
Isadora Silva de Carvalho, Lariane Angel Cepas, Álvaro Francisco Lopes de Sousa, Talita Morais Fernandes, Talia Gomes Luz, Jean Carlos Soares da Silva, Augusto da Silva Marques, Caíque Jordan Nunes Ribeiro, Shirley Veronica Melo Almeida Lima, Anderson Reis de Sousa, Carlos Arterio Sorgi, Ricardo Nakamura, Ana Paula Morais Fernandes   +12 more
doaj   +1 more source

Essential Updates 2024–2026: Advances in Colorectal Cancer Surgery

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Surgical innovation in colorectal cancer is increasingly judged not by technical feasibility alone, but by whether it improves oncological outcomes, preserves function, reduces morbidity, or makes difficult procedures more reproducible. This structured narrative review examines major surgical studies published from January 2024 through July ...
Hiroyasu Kagawa, Yusuke Kinugasa
wiley   +1 more source

Essential Updates in the Surgical Management of Inflammatory Bowel Disease: Current Topics From 2024 to Mid‐2026

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Inflammatory bowel disease management has undergone a major transformation with the introduction of treat‐to‐target strategies and highly effective biologic and small‐molecule therapies. Although these advances have reduced the overall requirement for surgery, operative intervention remains essential for selected patients with ulcerative ...
Yoshiki Okita, Tadanobu Shimura, Mikio Kawamura, Yuhki Koike, Yuji Toiyama   +4 more
wiley   +1 more source

Understanding Arthrogryposis Multiplex Congenita (AMC) Across the Lifespan: An Integrative Review of the Adult AMC Registry's Contributions With Lived Experience Partnerships

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT This reflective essay explores how collaborative work between researchers and adults living with Arthrogryposis Multiplex Congenita (AMC) has deepened and broadened our understanding of what it means to live with this rare condition. By intentionally integrating the lived experiences of individuals with AMC into research processes, the ...
Bonita J. Sawatzky, Megan K. MacGillivray, Tracey Schalk, William Bennett Mortenson   +3 more
wiley   +1 more source

Sexualized drug use and its association with sexual health among men who have sex with men in Cyprus

Ψυχολογία: το Περιοδικό της Ελληνικής Ψυχολογικής Εταιρείας
Sexualised drug use (SDU) i.e., the use of psychoactive substances in a sexual context, has been becoming the focus of researchers’ interest over the past years.
Antonios Poulios, Stavroula Triantafyllidou, Anna Apostolidou, Christos Krasidis, Ivonne Valdez Paez Petrou, Evi Kyprianou, Ioanna Yiasemi, Anna Papadaki, Christos Minas, Georgios Nikolopoulos, Chrysanthos Georgiou   +10 more
doaj   +1 more source

Public Attitudes Toward Compassionate Release of Older People From Prison: Findings From a National Survey in Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT The rapid increase in older people in prison populations worldwide is generating significant health, cost, and human rights pressures on custodial systems. Compassionate release for older, frail inmates is a potentially effective response, yet little is known about public support for this approach.
Ye In (Jane) Hwang, Natasha Ginnivan, Amanuel Kidane Hagos, Tony Butler   +3 more
wiley   +1 more source