Results 81 to 90 of about 14,613 (328)

Psychosexual Functioning of Cognitively-able Adolescents with Autism Spectrum Disorder Compared to Typically Developing Peers [PDF]

, 2017
To gain further insight into psychosexual functioning, including behaviors, intrapersonal and interpersonal aspects, in adolescents with Autism Spectrum Disorder (ASD), comprehensive, multi-informant measures are needed.
Dekker, L.P. (Linda), Ende, J. (Jan) van der, Greaves-Lord, K. (Kirstin), Louwerse, I. (Ilse), Maras, A. (Athanasios), Tick, N.T. (Nouchka), Vegt, E.J.M. (Esther) van der, Verhulst, F.C. (Frank)   +7 more
core   +1 more source

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

Advanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang, Yuchen Wang, Binbin Li, Xin Li, Chenyu Liu, Yanhao Chen, Cheng Tian, Dongmei Wang, Xiaosong Gu, Chunping Jiang, Yuda Wei, Qiurong Ding   +11 more
wiley   +1 more source

The effects of visual priming on information processing in child sexual offenders

, 2008
Child sexual offenders are hypothesized to hold offence-supportive beliefs that set them apart from others. The current study seeks support for this view via a cognitive-experimental approach.
Abel G. G., Barnett V., Beck A. T., Beech A. R., Copello A. G., Gannon T. A., Higgins E. T., Kirsten Keown, Mann R. E., Mann R. E., Murphy W. D., Theresa A. Gannon, Tony Ward, Welford A. T.   +13 more
core   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Sexualized drug use and its association with sexual health among men who have sex with men in Cyprus

Ψυχολογία: το Περιοδικό της Ελληνικής Ψυχολογικής Εταιρείας
Sexualised drug use (SDU) i.e., the use of psychoactive substances in a sexual context, has been becoming the focus of researchers’ interest over the past years.
Antonios Poulios, Stavroula Triantafyllidou, Anna Apostolidou, Christos Krasidis, Ivonne Valdez Paez Petrou, Evi Kyprianou, Ioanna Yiasemi, Anna Papadaki, Christos Minas, Georgios Nikolopoulos, Chrysanthos Georgiou   +10 more
doaj   +1 more source

Intimate partner violence, depression, and sexual behaviour among gay, bisexual and other men who have sex with men in the PROUD trial

BMC Public Health, 2019
Background Little is known about the prevalence and correlates of intimate partner violence (IPV) among gay, bisexual and other men who have sex with men (GBMSM) in the UK.
Ada R. Miltz, Fiona C. Lampe, Loraine J. Bacchus, Sheena McCormack, David Dunn, Ellen White, Alison Rodger, Andrew N. Phillips, Lorraine Sherr, Amanda Clarke, Alan McOwan, Ann Sullivan, Mitzy Gafos   +12 more
doaj   +1 more source

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

Kink in an English Field: The Drinking, Drug use and Sexual Practices of English Festival-Goers Who Engage in Kink [PDF]

, 2022
Mark McCormack, Fiona Measham, Maria Measham, Liam Wignall   +3 more
openalex   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Branded: Corporate Image, Sexual Stereotyping, and the New Face of Capitalism [PDF]

, 2007
In the context of unionized workforces covered by collective bargaining agreements, companies have-at most-been required to demonstrate a reasonable relationship between the grooming code and the business\u27s effort to project a corporate image that it ...
Avery, Dianne, Crain, Marion
core   +2 more sources