Results 91 to 100 of about 219,069 (299)

The cost of promiscuity: sexual transmission of Nosema microsporidian parasites in polyandrous honey bees [PDF]

, 2015
Multiple mating (and insemination) by females with different males, polyandry, is widespread across animals, due to material and/or genetic benefits for females.
AA Ptaszynska, AL Bourgeois, AP Lourenço, B Baer, B Baer, B Baer, BE Traver, BE Traver, BJ Cole, BP Oldroyd, C Alaux, C Yue, DC De Graaf, DR Tarpy, G Arnqvist, HR Mattila, I Fries, J Klee, JJ Boomsma, JL Li, JR de Miranda, KA Palmer, KE Roberts, KE Roberts, L Bourgeois, LW Simmons, M Higes, MA Furst, MD Jennions, ML Taylor, O Otti, P Graystock, P Graystock, P Graystock, RH Crozier, RJ Knell, RJ Paxton, S Sumner, T Chapman, TR Copley, W Wattanachaiyingcharoen, W-F Huang, WD Hamilton, WM Brooks, WOH Hughes, WOH Hughes, WOH Hughes, Y Chen, Y Chen, Y Peng, YP Chen   +50 more
core   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Integrated molecular, phenotypic and epidemiological surveillance of antimicrobial resistance in Neisseria gonorrhoeae in Germany

International Journal of Medical Microbiology
Numbers of infections with Neisseria gonorrhoeae are among the top three sexually transmitted infections (STI) worldwide. In addition, the emergence and spread of antimicrobial resistance (AMR) in Neisseria gonorrhoeae pose an important public-health ...
Kathleen Klaper, Hana Tlapák, Regina Selb, Klaus Jansen, Dagmar Heuer   +4 more
doaj   +1 more source

Abstinence Only vs. Comprehensive Sex Education: What are the Arguments? What is the Evidence? [PDF]

, 2002
Responding to the continuing health threats of HIV, STIs and unplanned pregnancy among young people, the widely respected Institute of Medicine of the National Academy of Sciences recently recommended eliminating congressional, federal, state and local ...
Chris Collins, Priya Alagiri, Stephen F. Morin, Todd Summers   +3 more
core  

Framework for better living with HIV in England [PDF]

, 2009
Duration: April 2007 - May 2009 Sigma Research was funded by Terrence Higgins Trust to co-ordinate the development of a framework to address the health, social care, support and information needs of people with diagnosed HIV in England.
Azad, Y, Carter, M, Crafer, E, Cregan, S, Keogh, P, Morley, C, Nkwenti, P, Nutland, W, Pebody, R, Reynolds, R, Summerside, J, Weatherburn, P   +11 more
core   +1 more source

A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis

Animal Models and Experimental Medicine, EarlyView.
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu, Yafei Yang, Chunxi Liu, Danting Wen, Tingyu Zhao, Ping Xie, Jing Xiao   +6 more
wiley   +1 more source

The basic reproduction number, $R_0$, in structured populations [PDF]

, 2019
In this paper, we provide a straightforward approach to defining and deriving the key epidemiological quantity, the basic reproduction number, $R_0$, for Markovian epidemics in structured populations.
Neal, Peter, Theparod, Thitiya
core   +2 more sources

Scalp electroacupuncture targeting trigeminal nerve activation alleviates post‐traumatic stress disorder–induced depression and neuroinflammation in mice

Animal Models and Experimental Medicine, EarlyView.
Scalp electroacupuncture (SA) through activation of the trigeminal pathway exerts anti‐inflammatory, antidepressant, and anxiolytic effects in an animal model of post‐traumatic stress disorder induced by single prolonged stress. This suggests that SA is involved in neuroinflammation and changes in brain‐derived neurotrophic factor protein through the ...
Bombi Lee, Yoongeun Kim, Hyungjun Kim, Dae‐Hyun Hahm   +3 more
wiley   +1 more source

Metformin enhances external urethral sphincter integrity and restores continence via AMPK activation in a rat model of stress urinary incontinence

Animal Models and Experimental Medicine, EarlyView.
The pathogenesis of stress urinary incontinence (SUI) is intimately associated with injury to the external urethral sphincter (EUS). In this study, we established an SUI model induced by double vaginal distension and demonstrated that metformin treatment activated the AMPK signaling in the EUS tissue.
Yuting Xu, Xuhong Li, Alvaro Munoz, Li Jiang, Lihua Huang, Yanhua Zhou, Liping Zhu, Youbo Yang   +7 more
wiley   +1 more source

Point of care tests for sexually transmitted infections (STIs) [PDF]

A number of clinical/disease areas have been prioritised by the Technology Strategy Board (TSB) and Department of Health (DH) for the DIIA Innovation Platform.
Osipenko, Leeza, Szczepura, Ala
core