Results 71 to 80 of about 226,749 (330)

Mapping the Non‐Canonical Splicing Variants: Decrypting the Hidden Genetic Architecture of Idiopathic Male Infertility

Advanced Science, EarlyView.
This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li, Yuge Chen, Dongdong Tang, Yuying Sheng, Xu Han, Hao Geng, Na Zhang, Zongliu Duan, Guanxiong Wang, Yang Gao, Rui Guo, Rong Hua, Zhiming Ding, Chuan Xu, Qunshan Shen, Zhen Yu, Bing Song, Mingrong Lv, Yuping Xu, Huan Wu, Ji Wu, Yunxia Cao, Xiaojin He   +22 more
wiley   +1 more source

Sexually Transmitted Diseases [PDF]

AAOHN Journal, 1986
D R, Owens, J T, Brown
openaire   +4 more sources

Buschke–Fischer–Brauer Keratoderma: A Case Report of a Rare Skin Disorder

Clinical Case Reports
Buschke–Fischer–Brauer keratoderma is a rare autosomal dominant disorder presenting as hyperkeratotic lesions on the palms and soles. Diagnosis requires clinical and histopathological evaluation. Management is symptomatic with keratolytics like salicylic
Dyala Sayed Ahmad, Rim Nasser, Moatasem Hussein Al‐janabi, Fouz Hassan   +3 more
doaj   +1 more source

Trends in sexually transmitted infections in general practice 1990-2000: population based study using data from the UK general practice research database [PDF]

, 2006
Objective: To describe the contribution of primary care to the diagnosis and management of sexually transmitted infections in the United Kingdom, 1990-2000, in the context of increasing incidence of infections in genitourinary medicine clinics ...
Brook, M.G., Cassell, J.A., Hayward, A.C., Hughes, G., Islam, A., Johnson, A.M., Kinghorn, G.R., Majeed, A., Mercer, C.H., Petersen, I., Ross, J.D., Simms, I., Stephenson, J.M., Sutcliffe, L.   +13 more
core  

The impact of contact tracing in clustered populations [PDF]

, 2010
The tracing of potentially infectious contacts has become an important part of the control strategy for many infectious diseases, from early cases of novel infections to endemic sexually transmitted infections. Here, we make use of mathematical models to
DM Green, DT Gillespie, E Volz, F Ball, IM Hall, IZ Kiss, IZ Kiss, J Clarke, J Müller, JC Miller, K Eames, KTD Eames, KTD Eames, Lauren Ancel Meyers, M Lipsitch, MA Serrano, Matt J. Keeling, MEJ Newman, MJ Keeling, MJ Keeling, MJ Keeling, MJ Tildesley, MR FitzGerald, MR Golden, NM Ferguson, NM Ferguson, R Huerta, S Bansal, S Riley, S Riley, T House, Thomas House   +31 more
core   +3 more sources

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

Advanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen, Xiaojuan Ge, Dongxu Fu, Haijun Mei, Feng Lv, Chao Yang, Jiahao Lu, Xiaozhong Shen, Bowen Li, Xiaoning Wang, Dong Liu   +10 more
wiley   +1 more source

Painful skin ulcers in psoriasis patients after taking methotrexate-containing traditional Chinese medicine: a retrospective case series

Frontiers in Allergy
BackgroundTraditional Chinese Medicine (TCM) has demonstrated certain efficacy in the treatment of psoriasis, a chronic papulosquamous skin disease. However, in rare instances, the use of TCM may exacerbate cutaneous lesions.
Yunhong Zheng, Yunhong Zheng, Yinzi Dubai, Ruizhe Wang, Suju Luo   +4 more
doaj   +1 more source

Nonviral Sexually Transmitted Diseases

Clinics in Colon and Rectal Surgery, 2019
AbstractThis article provides a practical overview for the management of nonviral sexually transmitted diseases affecting the perianal and anorectal regions. Clinical manifestations, diagnosis, and treatment of syphilis, gonorrhea, chancroid, donovanosis, and lymphogranuloma venereum are individually addressed.
Kyle G, Cologne, Christine, Hsieh
openaire   +3 more sources

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Human Papillomavirus: How Social Ideologies Influence Medical Policy and Care [PDF]

, 2012
The purpose of this paper is to discuss the ways in which new advances in the production of a vaccine against human papillomavirus (HPV) have been received by both the general public and the medical community.
Hachem, Fadi
core   +1 more source