Results 71 to 80 of about 2,570,952 (304)

A rapid isothermal CRISPR-Cas13a diagnostic test for genital herpes simplex virus infection

iScience
Summary: Prompt diagnosis is essential for managing herpes simplex virus types 1 and 2 (HSV-1/2). Existing diagnostic methods are not widely available that required expensive or additional equipment for conducting examinations and result readouts, which ...
Xiaona Yin, Hao Luo, Han Zhou, Ziyan Zhang, Yinyuan Lan, Zhanqin Feng, Wentao Chen, Heping Zheng   +7 more
doaj   +1 more source

Risk pathways for gonorrhea acquisition in sex workers: can we distinguish confounding from an exposure effect using a priori hypotheses? [PDF]

, 2014
The population distribution of sexually transmitted infections (STIs) varies broadly across settings. Although there have been many studies aiming to define subgroups at risk of infection that should be a target for prevention interventions by ...
Garnett, Geoffrey P, Gomez, GB, Ward, H, Gomez, Gabriela B, Ward, Helen, Gomez, Gabriela B., Garnett, GP, Garnett, Geoffrey P.   +7 more
core   +1 more source

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

Advanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng, Zijun Meng, Lan Wei, Pingjing Yang, Fanfan Zhang, Zhiyi Luo, Ting Lai, Chunli Li, Mengyao Zhao, Mengqin Xu, Jiaqi Wang, Linjun Li, Huarong Chen, Jin Li, Ailong Huang, Youquan Bu, Liuyang Zhao   +16 more
wiley   +1 more source

Functionally-informed fine-mapping identifies genetic variants linking increased CHD1L expression and HIV restriction in monocytes

Scientific Reports
Human Immunodeficiency Virus Type 1 (HIV) set-point viral load is a strong predictor of disease progression and transmission risk. A recent genome-wide association study in individuals of African ancestries identified a region on chromosome 1 ...
Riley H. Tough, Paul J. McLaren, The International Collaboration for the Genomics of HIV   +2 more
doaj   +1 more source

Rapid, low-cost, and portable molecular detection of HIV-1 subtype B and HCV 1a directly from blood

Microbiology Spectrum
Accessible molecular diagnostics for human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV) remain constrained by the cost and infrastructure requirements of existing molecular point-of-care platforms.
David M. Tang, Karen Michalak, Kelvin Nguyen, Philip Lacap, John Kim, Paul J. McLaren   +5 more
doaj   +1 more source

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

Advanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang, Xinyuan Li, Lixia Huang, Xiangcai Zhang, Wujian Ke   +4 more
wiley   +1 more source

Essential Updates in the Surgical Management of Inflammatory Bowel Disease: Current Topics From 2024 to Mid‐2026

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Inflammatory bowel disease management has undergone a major transformation with the introduction of treat‐to‐target strategies and highly effective biologic and small‐molecule therapies. Although these advances have reduced the overall requirement for surgery, operative intervention remains essential for selected patients with ulcerative ...
Yoshiki Okita, Tadanobu Shimura, Mikio Kawamura, Yuhki Koike, Yuji Toiyama   +4 more
wiley   +1 more source

1989 Sexually Transmitted Diseases Treatment Guidelines [PDF]

These guidelines for the treatment of patients with sexually transmitted diseases (STD) were established after consultation with a group of outside experts and staff of CDC.

core  

Reproductive health for refugees by refugees in Guinea II: sexually transmitted infections. [PDF]

, 2008
BACKGROUND: Providing reproductive and sexual health services is an important and challenging aspect of caring for displaced populations, and preventive and curative sexual health services may play a role in reducing HIV transmission in complex ...
Akaco Ekirapa, Souare, Yaya, Chen Mark I, Natasha Howard, Ekirapa, Akaco, Ekirapa Akaco, Mark I Chen, von Roenne Franz, von Roenne, Franz, von Roenne Anna, Chen, Mark I, von Roenne, Anna, Howard, Natasha, Howard Natasha, Franz von Roenne, Borchert Matthias, Anna von Roenne, Souare Yaya, Matthias Borchert, Yaya Souare, Borchert, Matthias   +20 more
core   +1 more source

B/ordering and healthcare access for migrants with precarious status: The role of healthcare workers in counteracting restrictive policies

American Journal of Community Psychology, EarlyView.
Abstract In Canada, precarious migration is largely invisibilized. Nonetheless, b/ordering greatly affects people's realities by limiting access to social rights. In Quebec, migrants with precarious status (MPS) do not have access to healthcare, although Quebec has a “universal” healthcare coverage.
Émilie Pigeon‐Gagné, Jill Hanley, Élise Bourgeois‐Guérin, Pénélope Boudreault   +3 more
wiley   +1 more source