Results 31 to 40 of about 2,148,996 (264)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genomic surveillance meets clinical practice: rule-based individualized treatment prediction for gonorrhoea using SensiTyper

open access: yesNature Communications
Extensively drug-resistant (XDR) Neisseria gonorrhoeae strains threaten the current empirical gonorrhoea treatment. We designed and analytically validated SensiTyper, a rule-based framework that predicts antimicrobial susceptibility from whole-genome ...
Daniel Golparian   +2 more
doaj   +1 more source

HUBUNGAN PENGETAHUAN DAN SIKAP DENGAN TINDAKAN PENCEGAHAN PENYAKIT MENULAR SEKSUAL PADA ANAK BUAH KAPAL DI PELABUHAN BELAWAN 2019

open access: yesJurnal Kebidanan Kestra, 2019
The act of the prevention sexually transmitted infections disease is one of to reduce the spread of sexually transmitted to live a sex safety and health life style.
Isroni Azhari Siregar   +2 more
doaj   +1 more source

Is the HCV-HIV co-infection prevalence amongst injecting drug users a marker for the level of sexual and injection related HIV transmission?

open access: yes, 2013
BACKGROUND: Amongst injecting drug users (IDUs), HIV is transmitted sexually and parenterally, but HCV is transmitted primarily parenterally. We assess and model the antibody prevalence of HCV amongst HIV-infected IDUs (denoted as HCV-HIV co-infection ...
?, ?   +9 more
core   +1 more source

Prevalence, risk factors, and uptake of interventions for sexually transmitted infections in Britain: findings from the National Surveys of Sexual Attitudes and Lifestyles (Natsal). [PDF]

open access: yes, 2013
BACKGROUND: Population-based estimates of prevalence, risk distribution, and intervention uptake inform delivery of control programmes for sexually transmitted infections (STIs).
Beddows, Simon   +33 more
core   +1 more source

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

open access: yesArthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram   +25 more
wiley   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

open access: yesAdvanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu   +13 more
wiley   +1 more source

In vitro selection and characterization of resistance to pristinamycin in Mycoplasma genitalium

open access: yesAntimicrobial Agents and Chemotherapy
Pristinamycin, a streptogramin combination, is recommended as a third-line treatment for Mycoplasma genitalium infections according to European guidelines. However, the molecular mechanisms underlying pristinamycin resistance have not yet been elucidated.
Chloé Le Roy   +7 more
doaj   +1 more source

Prevalence of Commonly Encountered Sexually Transmitted Infections Among Imprisoned Incarcerated Women [PDF]

open access: yesWomen’s Health Bulletin, 2014
Background: Sexually transmitted infections are major causes of morbidity among incarcerated women. However, little is known about the prevalence of these infections among female prisoners in Iran.
Shohreh Beheshti   +2 more
doaj   +1 more source

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