Results 201 to 210 of about 1,274,085 (313)

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

Sexually Transmitted Infections in adolescents and young adults: a growing public health challenge. [PDF]

Infez Med
Pipitò L, D'Agati G, Cascio A.
europepmc   +1 more source

Syphilis‐Associated Penile Lymphedema

JEADV Clinical Practice, EarlyView.
Amna Elyas, Valeska Padovese
wiley   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

An organotypic ectocervix mucosa model to study host-pathogen interaction of sexually transmitted infections. [PDF]

Mater Today Bio
Mehling H, Rousseau C, Krammer T, Leipold AM, Boyny A, Herbert SL, Wulff C, Saliba AE, Dölken L, Groeber-Becker F, Rudel T, Kessie DK.   +11 more
europepmc   +1 more source

“What Medical Management Should Be First Line for Bladder Storage Symptoms in NLUTD”—Pro Botox

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objectives Neurogenic lower urinary tract dysfunction (NLUTD) severely impairs patient quality of life (QoL). While oral medications are often first‐line treatments, their high failure rates and side effects limit their effectiveness. Thus, we argue for the use of intravesical botulinum toxin A (BoNT‐A) injections as a first‐line alternative ...
Vada Furlan, Alyssa Kobayashi, Zhina Sadeghi   +2 more
wiley   +1 more source

Computational phenotyping of sexually transmitted infections with the All of Us Research Program from 2010 to 2023. [PDF]

JAMIA Open
Shi F, Xia H, Weissman S, Li X, Yang X.
europepmc   +1 more source

Editorial: Sexually Transmitted Infections

The Open Infectious Diseases Journal, 2009
openaire   +1 more source

Bone Adaptation and Labor Organization in Co‐Located Medieval Anatolian Populations

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT Skeletal evidence from geographically co‐located populations offers a rare opportunity to disentangle subsistence‐driven bone adaptation from socially organized labor. This study examines upper limb morphology in two Byzantine communities—the urban center of Tyana (10th–13th c.
Gökhan Çakan, Ahmet G. Erdemir, Adalet E. Yıldız, Üstün Aydıngöz, Osman Doğanay, Ömür Dilek Erdal   +5 more
wiley   +1 more source

Southern African HIV Clinicians Society guideline on doxycycline post-exposure prophylaxis to prevent bacterial sexually transmitted infections. [PDF]

South Afr J HIV Med
Gill K, Kassim S, Brink A, Delany-Moretlwe S, Mazanderani AH, Hugo J, Kufa-Chakezha T, McIntyre J, Wattrus C, Bekker LG.   +9 more
europepmc   +1 more source