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Genetic alterations in Sezary syndrome

Leukemia & Lymphoma, 2011
Sezary syndrome (SS) is a rare form of cutaneous T-cell lymphoma characterized by erythroderma and the presence of Sezary cells in the skin, lymph nodes, and peripheral blood. Over the past few decades, cytogenetic and molecular cytogenetic findings have revealed many genetic alterations in patients with SS.
Katarzyna, Iżykowska   +1 more
openaire   +2 more sources

Mycosis Fungoides and Sezary Syndrome

Hematology/Oncology Clinics of North America, 2017
Mycosis fungoides and the Sezary syndrome (SS) are rare lymphomas of CD4+ helper T cells. There is stagewise progression from patch/plaques to thicker tumor lesions/diffuse erythroderma. Blood involvement is a characteristic of SS. Outcomes are related to the extent of skin, blood, lymph node, and visceral organ involvement. Patients with limited patch
Francine M, Foss, Michael, Girardi
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Functional Asplenia in Sezary Syndrome

Clinical Nuclear Medicine, 1980
A case of functional asplenia revealed by radiocolloid scanning is reported in a patient suffering from Sezary syndrome, a lymphoma of cutaneous origin. Heavy, diffuse sinusoidal infiltration of the spleen by the Sezary cells appears to be responsible for the functional asplenia in this case.
S, Balachandran, R, Kumar, T T, Kuo
openaire   +2 more sources

A case of the Sezary syndrome

Irish Journal of Medical Science, 1978
The clinical, heamatological and necropsy findings are described in a case of the Sezary syndrome. The comparative rarity of this entity is such that we are encouraged to publish the case, which we believe to be the first described in the Republic of Ireland.
J G, McCormack, P D, Holland, D, Pounder
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T Cell Erythroderma (Sezary Syndrome)

Archives of Dermatology, 1973
Acceptance of the Sezary syndrome was slow in the first two decades following its description, and the syndrome was confused with lymphoma cases with erythroderma in many reports. Taswell and Winkelmann1reported seven cases of erythroderma with atypical lymphocytosis in the skin and blood pointing out the clinical, histologic, and cytologic nature of ...
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A Case of Sezary Syndrome.

Nishi Nihon Hifuka, 1996
Sezary症候群の1例を報告した。43歳の女性, 約4年前に両手掌にそう痒性皮疹が出現し徐々に全身に拡大, 紅皮症状態となった。入院時, 全身に潮紅と鱗屑を認め頸部, 腋窩, 鼠径リンパ節を累々と触知した。末梢血液検査所見では白血球数84680/mm3と著明に増加し, CD4陽性細胞優位であった。電顕的に末梢血, 皮膚, リンパ節に脳回転様核を有するリンパ球を確認した。Sezary症候群と診断しメソトレキセート, プレドニゾロンの低量療法(MP療法)を行った。治療開始約1年後には白血球数はほぼ正常となり表在リンパ節もほとんど触知しなくなった。MP療法は比較的有効と考えられたが, 汎血球減少の出現によりメソトレキセートを中止したところ皮膚腫瘤の出現, リンパ節の腫脹を認め, LDHは急速に上昇 ...
Saburo ANZAI   +6 more
openaire   +1 more source

SEZARY'S SYNDROME.

British Journal of Dermatology, 1959
R A, MAIN, H B, GOODALL, W C, SWANSON
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SEZARY'S SYNDROME

Medical Journal of Australia, 1972
R A, Scamps   +2 more
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[The Sezary syndrome].

Recenti progressi in medicina, 1979
Dina MA   +5 more
openaire   +5 more sources

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