Results 51 to 60 of about 6,483 (201)

Sézary Syndrome: Different Erythroderma Morphological Features with Proposal for a Clinical Score System

Cells, 2022
Sézary syndrome is a rare subtype of cutaneous T-cell lymphoma characterized by erythroderma, peripheral lymphadenopathies, and circulating atypical cerebriform T-cells. To date, no definite staging system has been developed for these patients.
Gabriele Roccuzzo, Silvia Giordano, Gianluca Avallone, Marco Rubatto, Silvia Canonico, Ada Funaro, Erika Ortolan, Rebecca Senetta, Paolo Fava, Maria Teresa Fierro, Simone Ribero, Pietro Quaglino   +11 more
doaj   +1 more source

Prognostic significance of DNA cytometry in cutaneous malignant lymphomas. [PDF]

, 1991
The current classification of cutaneous malignant lymphomas (ML) into low-grade and high-grade lymphomas was found to be of limited reproducibility and permitted only a rough prediction about outcome.
Abmayr, Wolfgang, Braun-Falco, Otto, Burg, Günter, Dummer, Reinhard, Eckert, Fritjof, Kaudewitz, Peter, Stolz, Wilhelm, Vogt, Thomas   +7 more
core   +1 more source

Brentuximab vedotin and radiotherapy for CD30‐positive cutaneous T‐cell lymphoma – a retrospective multicenter analysis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives While brentuximab vedotin (BV) and radiotherapy (RTx) are established treatment options for CD30‐positive cutaneous T‐cell lymphoma (CTCL), data on their simultaneous or sequential use regarding efficacy and tolerability remain scarce.
Patrick Schummer, Caroline Glatzel, Philipp Schrüfer, Ingulf Lawrenz, Gabor Dobos, Ulrike Wehkamp, Svea Hüning, René Stranzenbach, Jan P. Nicolay, Matthias Goebeler, Marion Wobser   +10 more
wiley   +1 more source

Oligonucleotide array-CGH identifies genomic subgroups and prognostic markers for tumor stage mycosis fungoides [PDF]

, 2018
Mycosis fungoide (MF) patients who develop tumors or extracutaneous involvement usually have a poor prognosis with no curative therapy available so far.
Barranco, Carlos, Cigudosa, Juan Cruz, Dummer, Reinhard, Espinet Solà, Blanca, Estrach Panella, Ma. Teresa (María Teresa), Ferreira, Bibiana I., Gallardo, Fernando, Garcia-Muret, Maria P., Herrera, Marta, Karpova, Maria B., Muniesa Montserrat, Cristina, Ortiz Romero, Pablo L., Pujol, Ramon M., Romagosa, Vicenç, Salgado, Rocío, Salido Galeote, Marta, Serrano, Sergi, Servitje Bedate, Octavio, Solé Ristol, Francesc, Suela, Javier, Sánchez Schmidt, Júlia, Tensen, Cornelis P., Vermeer, Maarten H., Zipser, Marie C.   +23 more
core   +1 more source

Recent trends of incidence and mortality of cutaneous lymphomas in Germany

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Primary cutaneous lymphomas (PCL) are primarily composed of cutaneous T‐cell lymphomas (CTCL), followed by cutaneous B‐cell lymphomas (CBCL). This study aimed to assess the incidence and survival rates of PCL in Germany. Methods We analyzed data from the North Rhine‐Westphalia Cancer Registry (2008–2021), which covers a population of
Khodr Cheikh El Najjarine, Hiltraud Kajüter, Ina Wellmann, Andreas Stang, Chalid Assaf   +4 more
wiley   +1 more source

Current Opportunities for Treatment Optimization of Mycosis Fungoides and Sezary Syndrome

Клиническая онкогематология, 2018
Aim. To estimate vorinostat efficacy in patients with relapsed/refractory mycosis fungoides and Sezary syndrome. Materials & Methods. The total of 21 patients with refractory and progressive mycosis fungoides and Sezary syndrome receiving vorinostat ...
Natal’ya Gennad’evna Chernova, O. A. Kolomeitsev   +1 more
doaj   +1 more source

The PNH French Working Group Experience: Building a Strong Network of Cytometrists

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The PNH working group was created in 2010 to initiate a workshop on testing white blood cells to share international recommendations. Methods Thirty‐five French and Belgian laboratories equipped with 2‐ or 3‐laser cytometers applied three different panels with or without FLAER reagent in 305 samples.
Orianne Wagner‐Ballon, Magali Le Garff‐Tavernier, Rémi Lestestu, Bernard Drenou, Agathe Debliquis, the PNH French Working Group «CytHem‐HPN», Chantal Fossat, Claire Loosen, Bernard Chatelain, Marie Loosveld   +9 more
wiley   +1 more source

TOX Expression in Mycosis Fungoides and Sezary Syndrome

Diagnostics, 2022
Mycosis fungoides (MF) and Sezary syndrome (SS) are the two most common type of cutaneous T-cell lymphoma (CTCL). Currently, no markers can be clearly related to prognosis or to differential diagnosis between early stages and inflammatory benign diseases
Alessandro Pileri, Martina Cavicchi, Clara Bertuzzi, Simona Righi, Corrado Zengarini, Elena Sabattini, Giovanna Roncador, Claudio Agostinelli   +7 more
doaj   +1 more source

scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions

Journal of the European Academy of Dermatology and Venereology, EarlyView.
CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu, Agata Kurowski, Malini P. Naidu, Jonas Adalsteinsson, Shane A. Meehan, Natalia Alkon, Lauren R. Port, Sumanth Chennareddy, Emry R. Cohenour, Grace Christensen, Jonah Shulman, Nicholas Gulati, Constanze Jonak, Patrick M. Brunner   +13 more
wiley   +1 more source

Dermatology 2.0: Precision medicine for inflammatory skin diseases

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Digital immune mapping of transcriptomics profiles from inflammatory skin disease biopsies enables precise molecular diagnosis, quantification of immune modules and personalized therapy selection by matching dominant immune signatures to targeted treatments.
Jeremy Di Domizio, Antoine Girardin, Curdin Conrad, Teofila Seremet, Michel Gilliet   +4 more
wiley   +1 more source