Results 61 to 70 of about 6,483 (201)
Thymocyte selection-associated high mobility group box gene (TOX) is aberrantly over-expressed in mycosis fungoides and correlates with poor prognosis [PDF]
Mycosis fungoides (MF) often mimics the common chronic inflammatory skin diseases and is difficult to be diagnosed with certainty, partly because of the lack of well-characterized molecular markers.
Dutz, Jan P. +9 more
core +1 more source
Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal +3 more
wiley +1 more source
Guidelines on the use of extracorporeal photopheresis [PDF]
Peer ...
Arenberger, P. +39 more
core +1 more source
Extracorporeal photopheresis (ECP) induces apoptosis in circulating immune cells, but its kinetics vary slightly depending on the cell type. We compared the progression of apoptosis in PBMCs versus highly purified T cells exposed to 8‐methoxypsoralen and ultraviolet A.
Carlos Agustin Villegas‐Valverde +6 more
wiley +1 more source
Mycosis fungoides/Sezary's syndrome [PDF]
Review on Mycosis fungoides/Sezary's syndrome, with data on clinics, and the genes involved.
A Cuneo, GL Castoldi
openaire +1 more source
ABSTRACT Objectives To determine the diagnostic value of disclosing monotypic T‐cell populations by expression analysis of the constant region 1 of T‐cell receptor β (TRBC1) by flow cytometry, for the detection of T‐cell neoplasms, in a routine hematopathology practice setting.
Nilofar Rajabian +4 more
wiley +1 more source
Background Sézary syndrome is a rare and very aggressive leukemic variant of cutaneous T-cell lymphoma characterized by extensive skin involvement and a malignant circulating CD4+ T-cell clone which homes to the skin, over-expresses CD60, and lacks CD7 ...
Enrico Scala +10 more
doaj +1 more source
Diagnosis of cutaneous T-cell lymphoma by insurance type before and after the Affordable Care Act: a national database study [PDF]
The Affordable Care Act (ACT) was implemented to increase health care access and reduce the uninsured in the age group between pediatric and Medicare populations (18-64). The association of the ACA with insurance type upon diagnosis (uninsured, Medicaid,
Duvic, Madeleine +3 more
core
Suppressive CD8+ T‐Cells Are Key Cellular Mediators of Extracorporeal Photopheresis
ABSTRACT Extracorporeal photopheresis (ECP) is a widely utilized immunomodulatory procedure with an incompletely defined mechanism. In graft‐versus‐host disease (GvHD) and transplant rejection, ECP is thought to induce immune tolerance by increasing regulatory CD4+ T‐cells, whereas in cutaneous T cell lymphoa it may enhance dendritic cell–mediated ...
Kai J. Rogers +7 more
wiley +1 more source
Loss of the candidate tumor suppressor ZEB1 (TCF8, ZFHX1A) in Sézary syndrome [PDF]
Cutaneous T-cell lymphoma is a group of incurable extranodal non-Hodgkin lymphomas that develop from the skin-homing CD4+ T cell. Mycosis fungoides and Sézary syndrome are the most common histological subtypes.
Benucci, Roberto +9 more
core +2 more sources

