Results 71 to 80 of about 6,483 (201)
Sezary syndrome: diagnosis and management
Journal of the Royal College of Physicians of Edinburgh, 2012 We describe a case of a delayed diagnosis of Sezary syndrome in a patient with longstanding generalised pruritus, erythroderma, alopecia and nail dystrophy. We highlight some of the difficulties in diagnosis despite the fact that all patients have a characteristic circulating malignant T-cell lymphocyte in peripheral blood.
C, Ogilvie +3 more
openaire +2 more sources
Primary Cutaneous Peripheral T‐Cell Lymphoma With Follicular Helper T‐Cell Phenotype
Journal of Cutaneous Pathology, Volume 53, Issue 2, Page 147-152, February 2026.ABSTRACT An otherwise healthy 82‐year‐old woman presented with recurrent, asymptomatic erythematous papulo‐nodular lesions on the face and extremities. A skin biopsy revealed a dense, non‐epidermotropic lymphohistiocytic infiltrate with granulomatous features and a mixed population of medium‐sized atypical lymphoid cells and plasma cells ...
Nidia Planella‐Fontanillas +9 more
wiley +1 more source
Cutaneous primary B-cell lymphomas: from diagnosis to treatment [PDF]
, 2015 Primary cutaneous B-cell lymphomas are a heterogeneous group of mature B-cells neoplasms with tropism for the skin, whose biology and clinical course differ significantly from the equivalent nodal lymphomas.
Lima, M.
core +3 more sources
The FEBS Journal, Volume 293, Issue 3, Page 749-765, February 2026.A genome‐wide CRISPR‐Cas9 screen identified H3K27 methylation as a key regulator of T‐cell lymphoma sensitivity to dimethyl fumarate (DMF). Specifically, inhibition of enhancer of zeste homolog 2 (EZH2) enhanced DMF‐induced cell death in malignant T cells. These results provide functional evidence for the role of EZH2 in modulating drug sensitivity and
Jan P. Teubner +17 more
wiley +1 more source
The Prognostic Value of ТР53 Gene Mutations in Patients with Cutaneous T-Cell Lymphomas
Клиническая онкогематологияBACKGROUND. Primary cutaneous lymphomas represent a heterogeneous group of neoplastic diseases with unique clinical, immunomorphological, and molecular genetic features.
Liliya Gamilevna Gorenkova +3 more
doaj +1 more source
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 2, Page 174-184, February 2026.This EBMT Practice Harmonisation and Guidelines Committee consensus provides practical recommendations for the selection, timing and conduct of allogeneic transplantation in advanced‐stage mycosis fungoides and Sézary syndrome, aiming to optimize outcomes through early multidisciplinary collaboration and evidence‐based decision‐making.
Gandhi Damaj +26 more
wiley +1 more source
Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell-derived lymphomas. [PDF]
, 2016 Angioimmunoblastic T-cell lymphoma (AITL) and other lymphomas derived from follicular T-helper cells (TFH) represent a large proportion of peripheral T-cell lymphomas (PTCLs) with poorly understood pathogenesis and unfavorable treatment results.
Bernard, Olivier +27 more
core +3 more sources
The Journal of Pathology: Clinical Research, Volume 12, Issue 1, January 2026.Abstract Adult T‐cell leukemia/lymphoma (ATLL) is a distinct type of peripheral T‐cell lymphoma (PTCL) driven by human T‐lymphotropic virus type I (HTLV‐1)–infected T cells, but diagnosis can be confounded by histological overlap with non‐ATLL PTCL. While molecular testing is the diagnostic gold standard in endemic areas, HTLV‐1/2 serology is often ...
Chang‐Tsu Yuan +10 more
wiley +1 more source
Cutaneous T-cell lymphoma: Differential diagnostics of erythrodermic conditions
Vestnik Dermatologii i Venerologii, 2019 Erythroderma is a condition damaging at least 80–90 % of the skin surface, characterized by erythema and peeling. This condition may be a manifestation of various diseases of the skin and internal organs, including malignant lymphoproliferative disorders.
A. E. Karamova +3 more
doaj +1 more source