Results 41 to 50 of about 22,318 (164)

Evaluation of insecticidal potential of organochemicals on SF9 cell line

Journal of Basic and Applied Zoology, 2021
Background Organophosphates and Pyrethroids are the most widely used pesticides worldwide and are known to have significant toxicity on the nervous system of the target pest.
Nishi Pandya, Bhumi Thakkar, Parth Pandya, Pragna Parikh   +3 more
doaj   +1 more source

Long-Read High-Throughput Sequencing (HTS) Revealed That the Sf-Rhabdovirus X⁺ Genome Contains a 3.7 kb Internal Duplication

Viruses, 2023
We previously reported a novel rhabdovirus produced from the Spodoptera frugiperda Sf9 cell line, designated as Sf-rhabdovirus X+ since it contained a unique accessory gene X.
Hailun Ma, Trent J. Bosma, Arifa S. Khan
doaj   +1 more source

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

Advanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee, Yejin Jang, Yujin Kim, Yumi Shin, Ji‐Joon Song, Meehyein Kim, Sangyong Jon   +6 more
wiley   +1 more source

Extra-viral DNA in adeno-associated viral vector preparations induces TLR9-dependent innate immune responses in human plasmacytoid dendritic cells

Scientific Reports, 2023
Adeno-associated viral (AAV) vector suspensions produced in either human derived HEK cells or in Spodoptera frugiperda (Sf9) insect cells differ in terms of residual host cell components as well as species-specific post-translational modifications ...
Kirsten Bucher, Eduardo Rodríguez-Bocanegra, Bernd Wissinger, Torsten Strasser, Simon J. Clark, Andreas L. Birkenfeld, Dorothea Siegel-Axel, M. Dominik Fischer   +7 more
doaj   +1 more source

Spodoptera frugiperda Sf9 cells as a model system to investigate the role of detoxification gene expression in response to xenobiotics

Current Research in Insect Science, 2022
Spodoptera frugiperda (fall armyworm) is a highly destructive invasive pest that feeds on numerous crops including maize and rice. It has developed sophisticated mechanisms to detoxify xenobiotics such as secondary plant metabolites as well as manmade ...
Dries Amezian, Sonja Mehlhorn, Calypso Vacher-Chicane, Ralf Nauen, Gaëlle Le Goff   +4 more
doaj   +1 more source

Gut Microbe‐Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation

Advanced Science, EarlyView.
Acinetobacter regulates dinotefuran tolerance in Propylea japonica by mediating the expression of the horizontally transferred gene PjDUF1. Abstract Insect–microbial symbiont relationships are widespread in nature and often involve lateral gene transfer.
Ningbo HuangFu, Xiangzhen Zhu, Zhijuan Tang, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Jinjie Cui, Zhaojiang Guo, Junyu Luo, Xueke Gao   +10 more
wiley   +1 more source

Exploring the Comprehensive Kozak Sequence Landscape for AAV Production in Sf9 System

Viruses, 2023
The widespread successful use of recombinant Adeno-associated virus (rAAV) in gene therapy has driven the demand for scale-up manufacturing methods of vectors with optimized yield and transduction efficiency.
Oleksandr Kondratov, Sergei Zolotukhin
doaj   +1 more source

Molecular bases of insect odorant receptor function: specificity and evolution

Biological Reviews, EarlyView.
ABSTRACT Insect odorant receptors (ORs) are a class of chemoreceptors that insects use to detect volatile cues in their environment. In recent years, major advances in the field of structural biology have made it possible to obtain the first structures of insect ORs.
Zibo Li, Abhinob Baruah, Sridevi Bhamidipati, Nicolas Montagné, Emmanuelle Jacquin‐Joly, Camille Meslin   +5 more
wiley   +1 more source

Safety, immunogenicity and protective effectiveness of heterologous boost with a recombinant COVID-19 vaccine (Sf9 cells) in adult recipients of inactivated vaccines

Signal Transduction and Targeted Therapy
Vaccines have proven effective in protecting populations against COVID-19, including the recombinant COVID-19 vaccine (Sf9 cells), the first approved recombinant protein vaccine in China.
Wenxin Luo, Jiadi Gan, Zhu Luo, Shuangqing Li, Zhoufeng Wang, Jiaxuan Wu, Huohuo Zhang, Jinghong Xian, Ruixin Cheng, Xiumei Tang, Yi Liu, Ling Yang, Qianqian Mou, Xue Zhang, Yi Chen, Weiwen Wang, Yantong Wang, Lin Bai, Xuan Wei, Rui Zhang, Lan Yang, Yaxin Chen, Li Yang, Yalun Li, Dan Liu, Weimin Li, Lei Chen   +26 more
doaj   +1 more source

Dataset on recombinant expression of an ancient chitinase gene from different species of Leishmania parasites in bacteria and in Spodoptera frugiperda cells using baculovirus

Data in Brief, 2020
The data presented here is related to negative results obtained with the recombinant expression of chitinase from four species of Leishmania parasites in two expression systems, performed in order to investigate the molecular characteristics of the ...
Aline Diniz Cabral, Felipe Baena Garcia, Rodrigo Buzinaro Suzuki, Tanil Lacerda Góis Filho, Renata Torres da Costa, Ligia Marinho Pereira Vasconcelos, Edmar Silva Santos, Márcia Aparecida Sperança   +7 more
doaj   +1 more source