PHB2 affects the virulence of Vip3Aa to Sf9 cells through internalization and mitochondrial stability [PDF]
Virulence, 2022 The vegetative insecticidal proteins (Vip3A) secreted by some Bacillus thuringiensis (Bt) strains during vegetative growth are regarded as a new generation of insecticidal toxins. Like insecticidal crystal proteins, they are also used in transgenic crops
Baoju An +5 more
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Safety, immunogenicity and protective effectiveness of heterologous boost with a recombinant COVID-19 vaccine (Sf9 cells) in adult recipients of inactivated vaccines [PDF]
Signal Transduction and Targeted TherapyVaccines have proven effective in protecting populations against COVID-19, including the recombinant COVID-19 vaccine (Sf9 cells), the first approved recombinant protein vaccine in China.
Wenxin Luo +26 more
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DnaJ homolog subfamily A member1 (DnaJ1) is a newly discovered anti-apoptotic protein regulated by azadirachtin in Sf9 cells [PDF]
BMC Genomics, 2018 Background Azadirachtin, one of the most promising botanical insecticides, has been widely used for pest control. Azadirachtin induces apoptosis in insect cell lines, including Sf9, SL-1 and BTI-Tn-5B1–4.
Benshui Shu +5 more
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dsRNase1 contribution to dsRNA degradation activity in the Sf9 cells conditioned medium. [PDF]
Front Insect Sci, 2023 RNA interference (RNAi) is inefficient in lepidopteran insects, including Spodoptera frugiperda. RNase activity in the lumen and hemocoel is known to contribute to low RNAi efficiency in these insects.
Koo J, Palli SR.
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RNAi in Spodoptera frugiperda Sf9 Cells via Nanomaterial Mediated Delivery of dsRNA: A Comparison of Poly-l-arginine Polyplexes and Poly-l-arginine-Functionalized Au Nanoparticles. [PDF]
ACS Appl Mater Interfaces, 2020 This work focused on the delivery of dsRNA either complexed with poly-L-arginine (PLR-polyplex) or loaded onto poly-L-arginine functionalized 20 nm Au nanoparticles (PLR/Au NPs).
Laisney J +4 more
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Stability of selected reference genes in Sf9 cells treated with extrinsic apoptotic agents. [PDF]
Sci Rep, 2019 As a tightly controlled cell death process, apoptosis eliminates unwanted cells and plays a vital role in multicellular organisms. Previous study have demonstrated that apoptosis occurred in Spodoptera frugiperda cultured Sf9 cells, which triggered by ...
Shu B, Zhang J, Zeng J, Cui G, Zhong G.
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Cytotoxic and Apoptotic Activity of the Novel Harmine Derivative ZC-14 in Sf9 Cells. [PDF]
Int J Mol Sci, 2018 Harmine, one of the natural β-carboline alkaloids extracted from Peganum harmala L., exhibits broad spectrum but limited insecticidal ability against many pests. So there is an urgent need to synthesize novel derivatives with high efficiency.
Zhang J, Zhang Z, Shu B, Cui G, Zhong G.
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Autophagy induced by Vip3Aa has a pro-survival role in Spodoptera frugiperda Sf9 cells [PDF]
Virulence, 2021 Vip3Aa is an insecticidal protein that can effectively control certain lepidopteran pests and has been used widely in biological control. However, the mechanism of action of Vip3Aa is unclear.
Xiaoyue Hou, Lu Han, Baoju An, Jun Cai
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Impact of Inverted Terminal Repeat Integrity on rAAV8 Production Using the Baculovirus/Sf9 Cells System. [PDF]
Hum Gene Ther Methods, 2017 Adeno-associated virus (AAV) inverted terminal repeats (ITRs) are key elements of AAV. These guanine-cytosine-rich structures are involved in the replication and encapsidation of the AAV genome, along with its integration in and excision from the host ...
Savy A +5 more
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Transcriptome analysis of Spodoptera frugiperda Sf9 cells reveals putative apoptosis-related genes and a preliminary apoptosis mechanism induced by azadirachtin. [PDF]
Sci Rep, 2017 As an important botanical pesticide, azadirachtin demonstrates broad insecticidal activity against many agricultural pests. The results of a previous study indicated the toxicity and apoptosis induction of azadirachtin in Spodoptera frugiperda Sf9 cells.
Shu B +5 more
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