Results 91 to 100 of about 10,688,777 (228)
SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activities [PDF]
, 1997 Traversal from G1 to S-phase in cycling cells of budding yeast is dependent on the destruction of the S-phase cyclin/CDK inhibitor SIC1. Genetic data suggest that SIC1 proteolysis is mediated by the ubiquitin pathway and requires the action of CDC34 ...
Deshaies, Raymond J. +2 more
core
RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
MedComm – Oncology, Volume 5, Issue 1, March 2026.Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang +6 more
wiley +1 more source
The Journal of General Physiology, 2012 The inositol 1,4,5-trisphosphate (IP3) receptor (IP3R) channel is crucial for the generation and modulation of intracellular Ca2+ signals in animal cells. To gain insight into the complicated ligand regulation of this ubiquitous channel, we constructed a
G. Ullah, Don-On Daniel Mak, J. Pearson
semanticscholar +1 more source
ChemistryOpen, Volume 15, Issue 2, February 2026.Polygonum cognatum extracts exhibit strong antioxidant, anti‐inflammatory, antidiabetic, and antimicrobial activities. This study demonstrates, for the first time, histone deacetylase inhibitory activity, revealing epigenetic modulation potential.
Serhat Karaman +2 more
wiley +1 more source
The Effect of MicroRNA bantam on Baculovirus AcMNPV Infection in Vitro and in Vivo
Viruses, 2016 The role of microRNA bantam, one of the most abundant microRNAs in Sf9 cells, was studied for its role in baculovirus infection in vitro and in vivo.
Xiaojie Shi +4 more
doaj +1 more source
Data in Brief, 2020 The data presented here is related to negative results obtained with the recombinant expression of chitinase from four species of Leishmania parasites in two expression systems, performed in order to investigate the molecular characteristics of the ...
Aline Diniz Cabral +7 more
doaj +1 more source
Efficient and rapid isolation of native AMPA receptor complexes for cryo‐EM
Protein Science, Volume 35, Issue 2, February 2026.Abstract Isolating native ion channels for structural characterization is routinely achieved by extraction from membrane fractions of tissue with prolonged mild detergent treatment. AMPA receptors (AMPARs), glutamatergic receptors that mediate fast excitatory transmission and synaptic plasticity, are coassembled with diverse auxiliary subunits and ...
Jumi Park, Eric Gouaux
wiley +1 more source
Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer: a novel mechanism for enhancing specific antigen presentation [PDF]
, 2007 The B cell antigen receptor (BCR) efficiently facilitates the capture and processing of a specific antigen for presentation on MHC class II molecules to antigen specific CD4+ T cells (1).
Ben J. C. Quah +5 more
core +2 more sources
Functional characterization of NRT1/PTR FAMILY transporters: looking for a needle in a haystack
New Phytologist, Volume 249, Issue 3, Page 1124-1144, February 2026.Summary NRT1/PTR FAMILY (NPF) transporters play crucial roles in plant physiology and development due to their involvement in nitrogen nutrition and their ability to transport multiple signaling molecules and metabolites. Whereas most eukaryotic and prokaryotic NPF orthologs are peptide transporters, most flowering plant NPF transport other substrates ...
Laura Morales de Los Ríos +6 more
wiley +1 more source
Human Papillomavirus Type16- L1 VLP Production in Insect Cells [PDF]
Iranian Journal of Basic Medical Sciences, 2013 Objective(s): Infection by high-risk papillomavirus is regarded as the major risk factor in the development of cervical cancer. Recombinant DNA technology allows expression of the L1 major capsid protein of HPV in different expression systems, which has
Asghar Abdoli +4 more
doaj