Results 211 to 220 of about 84,471 (250)

Phenotype Refinement Influences GWAS‐Implicated Variant Effect Sizes for Insomnia

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT How phenotypes are measured, especially when relying on subjective reports, is an impediment to the utility of genome‐wide association studies (GWAS). This is a common problem in GWAS for sleep traits, as many sleep disturbances appear subjectively similar despite having distinct underlying pathophysiology.
Amber J. Zimmerman   +7 more
wiley   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

open access: yesObesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey   +7 more
wiley   +1 more source

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

open access: yesObesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid   +22 more
wiley   +1 more source

Comparative Evaluation of Treatment Effectiveness in Skeletal Class III Malocclusion: Surgery‐First Approach Using Clear Aligners Versus Fixed Appliances

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective This study aimed to assess treatment outcomes, identify predictors of relapse in skeletal Class III patients treated with the surgery‐first approach (SFA), comparing fixed appliances (FA) with invisalign clear aligners (CA). Materials and Methods Forty adult patients treated with bimaxillary surgery and SFA were retrospectively ...
Yang Zhou   +3 more
wiley   +1 more source

Hepatoprotective effects of astaxanthin and kokum on lipid peroxidation and fatty acid profile in mice with diet-induced NAFLD. [PDF]

open access: yesFront Pharmacol
Ksepka N   +6 more
europepmc   +1 more source

Obesity and Oral Health‐Related Quality of Life: An Exploratory Analysis of Associated Factors

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives This study assessed oral health‐related quality of life in individuals with and without obesity, and investigated its association with socioeconomic‐demographic characteristics, lifestyle habits, health conditions, and clinical care.
Ana Karina de Oliveira de Santana Barros   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy