Phenotype Refinement Influences GWAS‐Implicated Variant Effect Sizes for Insomnia
ABSTRACT How phenotypes are measured, especially when relying on subjective reports, is an impediment to the utility of genome‐wide association studies (GWAS). This is a common problem in GWAS for sleep traits, as many sleep disturbances appear subjectively similar despite having distinct underlying pathophysiology.
Amber J. Zimmerman +7 more
wiley +1 more source
Feasibility of Immersive Virtual Reality for Delivering Semantic Feature Analysis to Adults with Communication Disorders and Normal Cognitive Aging. [PDF]
Harvey J, Cuellar ME, Chang YI.
europepmc +1 more source
Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
A PUFA-rich diet increases endogenous genotoxic stress and mitochondrial DNA damage in mice. [PDF]
Shimizu M +4 more
europepmc +1 more source
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid +22 more
wiley +1 more source
Crossbreeding a Mediterranean Local Chicken Breed with a Medium-Growing Commercial Hybrid as a Complementary Strategy for Conservation and Productive Valorization: Growth Performance, Carcass Traits, and Meat Quality. [PDF]
Martínez-Martínez L +5 more
europepmc +1 more source
ABSTRACT Objective This study aimed to assess treatment outcomes, identify predictors of relapse in skeletal Class III patients treated with the surgery‐first approach (SFA), comparing fixed appliances (FA) with invisalign clear aligners (CA). Materials and Methods Forty adult patients treated with bimaxillary surgery and SFA were retrospectively ...
Yang Zhou +3 more
wiley +1 more source
Hepatoprotective effects of astaxanthin and kokum on lipid peroxidation and fatty acid profile in mice with diet-induced NAFLD. [PDF]
Ksepka N +6 more
europepmc +1 more source
Obesity and Oral Health‐Related Quality of Life: An Exploratory Analysis of Associated Factors
ABSTRACT Objectives This study assessed oral health‐related quality of life in individuals with and without obesity, and investigated its association with socioeconomic‐demographic characteristics, lifestyle habits, health conditions, and clinical care.
Ana Karina de Oliveira de Santana Barros +15 more
wiley +1 more source
Whole-Blood Fatty Acid Phenotypes and Subsequent Quality-of-Life Changes Among Cancer Survivors. [PDF]
Lv L +7 more
europepmc +1 more source

