Results 51 to 60 of about 4,667 (194)

Debunk the Myth of SFT Generalization

CoRR
A prevailing view holds that supervised fine-tuning (SFT) memorizes training data and fails to generalize, whereas reinforcement learning (RL) attains broader robustness. We revisit this claim through a systematic evaluation on two decision-making benchmarks, Sokoban and General Points, and arrive at a different conclusion.
Xiaofeng Lin, Hejian Sang, Zhipeng Wang, Xuezhou Zhang   +3 more
openaire   +2 more sources

Predominance of In‐Field Recurrence After Radiotherapy for Sinonasal Cancer: A Single‐Center Retrospective Study

Head &Neck, EarlyView.
ABSTRACT Background Sinonasal malignancies (SNM) are rare, heterogeneous tumors with poor prognosis. There is an unmet need to improve treatment outcomes. Despite advances in imaging and molecular classification, optimal curative radiotherapy (RT) strategies remain undefined.
M. de Ridder, L. J. van de Velde, T. de Bie, R. van Noortwijk, C. P. J. Raaijmakers, E. H. Voormolen, W. W. Braunius, R. de Bree, G. E. Breimer, L. A. Devriese, E. J. Smid, J. A. Rijken   +11 more
wiley   +1 more source

Immune profiling and prognosis implications in severe fever with thrombocytopenia syndrome with and without hemophagocytic lymphohistiocytosis

Travel Medicine and Infectious Disease
Objective: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease with high mortality, particularly when complicated by hemophagocytic lymphohistiocytosis (HLH).
Siyu Zou, Ting Wang, Danning Xu, Wei Wei, Yun Wang, Ming Huang, Shiji Wu, Feng Wang, Hongyan Hou   +8 more
doaj   +1 more source

Medical Reasoning With Large Language Models: A Systematic Review and Evaluation

iNew Medicine, EarlyView.
ABSTRACT Large language models (LLMs) have achieved strong performance on medical exam–style tasks, motivating growing interest in their deployment in real‐world clinical settings. However, clinical decision‐making is inherently safety‐critical, context‐dependent, and conducted under evolving evidence.
Xiaohan Ren, Chenxiao Fan, Wenyin Ma, Hongliang He, Chongming Gao, Xiaoyan Zhao, Fuli Feng   +6 more
wiley   +1 more source

High CRP/PNI levels predict an unfavorable prognosis in severe fever with thrombocytopenia syndrome: A propensity score matching study

Immunity, Inflammation and Disease
Background This study aimed to identify a novel inflammatory index and construct a nomogram for predicting in‐hospital mortality due to severe fever with thrombocytopenia syndrome (SFTS).
Chunxia Guo, Huan Wang, Xiaorong Wang, Shan Tian   +3 more
doaj   +1 more source

Effect of fasting plasma glucose level in severe fever and thrombocytopenia syndrome patients without diabetes.

PLoS Neglected Tropical Diseases
Hyperglycemia is correlated with worse in-hospital outcomes in acute infectious diseases such as coronavirus disease 2019 (COVID-19) and severe fever with thrombocytopenia syndrome (SFTS).
Jun Pan, Zhihao Yang, Wen Xu, Shan Tian, Xiaobo Liu, Chunxia Guo   +5 more
doaj   +1 more source

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

Interdisciplinary Medicine, EarlyView.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao, Xiaowei Chang, Jun Zhang, Yinshan Hong, Wenhui Cao, Zhewu Zhao, Yu‐E. Wang, Yanling Yang   +7 more
wiley   +1 more source

Designing γ‐TiAl Alloys With Refined Twin‐Lamellar Microstructures via Machine Learning‐Driven Phase‐Field Methods

Materials Genome Engineering Advances, EarlyView.
Dual‐phase γ‐TiAl alloys with refined twin‐lamellar (RTL) structures exhibit optimal strength‐ductility synergy. Here, phase‐field simulations reveal composition‐stress‐dependent refined twin‐lamellar (RTL) microstructure evolution. Machine learning (CatBoost + NSGA‐III) trained on phase‐field images predicts optimal RTL‐stress‐composition design space.
Jianwei Li, Zhenqiang Xiong, Chuanxin Liang, Tianjiao Dong, Heran Wang, Mengyuan Hao, Liqiang He, Tianlong Zhang, Dong Wang   +8 more
wiley   +1 more source

Prognostic Factors of Severe Fever with Thrombocytopenia Syndrome in South Korea

Viruses, 2020
Severe fever with thrombocytopenia syndrome (SFTS), a tick-borne infectious disease, is difficult to differentiate from other common febrile diseases.
Misun Kim, Sang Taek Heo, Hyunjoo Oh, Suhyun Oh, Keun Hwa Lee, Jeong Rae Yoo   +5 more
doaj   +1 more source

DEET‐cyclodextrin inclusion complexes for mosquito and tick repellency: Extended repellency time and no zebrafish embryotoxicity

Pest Management Science, EarlyView.
Hydroxypropyl‐β‐cyclodextrin (HPβCD)–N,N‐diethyl‐meta‐toluamide (DEET) complex extended tick repellency to 168 h. Full protection against Aedes aegypti for 7 h with HPβCD‐DEET. HPβCD reduced DEET release and skin retention significantly. No embryotoxicity observed below 325 mg L−1 in zebrafish model.
Gessyka Rayana Silva Pereira, Gleidson Cardoso, Maria Luiza Kuhn Camargo, Michele Resende Machado, Mayara Macedo Barrozo, Juscelino Rodrigues, Gisele Augusto Rodrigues de Oliveira, Caio Monteiro, Christian Luz, Ricardo Neves Marreto, Stephânia Fleury Taveira   +10 more
wiley   +1 more source