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The hnRNP A2B1 is important for the replication of SFTSV and other RNA viruses
Microbiology SpectrumABSTRACT The heterogeneous nuclear ribonucleoprotein (hnRNP A2B1) is a key component of the hnRNP complex involving RNA modulation in eukaryotic cells and it has also been reported to be involved in the replication of the hepatitis E virus, influenza A virus, and hepatitis B virus.
Chuan-Min Zhou, Xuejie Yu, Binyan Liu
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SFTSV NSs Sequesters the Complex of SFTSV NP‐SAFA to Suppress SAFA Mediated Immune Response
Journal of Medical VirologyABSTRACT Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging pathogenic Bunyavirus with a fatality rate of up to 30%. SFTSV nonstructural protein (NSs) forms viroplasm‐like structures in the cytoplasm of infected cells, sequestering antiviral proteins ...
Xin‐bo Huang +10 more
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Preparation of a polyclonal antibody against the non-structural protein, NSs of SFTSV
Protein Expression and Purification, 2021Severe fever with thrombocytopenia syndrome virus (SFTSV) is newly discovered virus which is the member of the order Bunyavirales, family phenuiviridae, phlebovirus genus. Its genome is composed of 3 segments of negative-sense RNA L, M and S. NSs is a non structure protein encoded by S segment which is important for viral replication and virulence. NSs
Yong Gang Li
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2019
At first, the basic structures of the viral genomes of severe fever with thrombocytopenia syndrome virus (SFTSV) and related viruses are shown. Then the structures and functions of structural and nonstructural proteins of SFTSV are discussed. Finally, recent information relating to the basic property of SFTSV, cytopathic effect, plaque formation and ...
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At first, the basic structures of the viral genomes of severe fever with thrombocytopenia syndrome virus (SFTSV) and related viruses are shown. Then the structures and functions of structural and nonstructural proteins of SFTSV are discussed. Finally, recent information relating to the basic property of SFTSV, cytopathic effect, plaque formation and ...
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Experimental Infection of Ticks with SFTSV
Many members in the class Bunyaviricetes are tick-borne viruses. Experimental viral infection of ticks is greatly needed to better understand the tick-virus interactions. To date, multiple laboratory techniques for the viral infection of ticks have been documented.Jiao, Xu, Xue-Jie, Yu
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Molecular Epidemiology of SFTSV
2019Indigenous severe fever with thrombocytopenia syndrome (SFTS) has been reported to be endemic to China, South Korea, and Japan. To date, several molecular epidemiology and phylogenetic studies of SFTS virus (SFTSV) have been performed. At the beginning of this review, the impact of the source of the samples (i.e., patient specimens vs.
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2019
Severe fever with thrombocytopenia syndrome (SFTS) caused by SFTS virus (SFTSV), a novel phlebovirus, was reported to be endemic to central and northeastern China, South Korea, and Japan. SFTS is a tick-borne viral infection with high morbidity and mortality. SFTSV is circulating in nature in the SFTS-endemic areas.
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Severe fever with thrombocytopenia syndrome (SFTS) caused by SFTS virus (SFTSV), a novel phlebovirus, was reported to be endemic to central and northeastern China, South Korea, and Japan. SFTS is a tick-borne viral infection with high morbidity and mortality. SFTSV is circulating in nature in the SFTS-endemic areas.
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Genome-based analysis of SFTSV causing severe encephalitis with brain lesions
Journal of NeuroVirology, 2019Encephalitis is an infrequent manifestation in the various spectrums caused by severe fever with thrombocytopenia syndrome virus (SFTSV) infection. There are few data about the possible pathogenic mechanisms of SFTSV-associated encephalitis. Here, two SFTSV-infected patients with onset of encephalitis were enrolled.
Chunjuan, Wang +8 more
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Errors in the deposited SFTSV L protein structure
Nature Microbiology, 2021Stephen Cusack, Maria Rosenthal
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Reply to: Errors in the deposited SFTSV L protein structure
Nature Microbiology, 2021Panpan Wang +3 more
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