Results 31 to 40 of about 68,716 (153)

Metal Ions and Chemical Modification Reagents Inhibit the Enzymatic Activity of Lecithin-Dependent Hemolysin from Vibrio parahaemolyticus

Toxins, 2022
Lecithin-dependent thermolabile hemolysin (LDH) is a virulence factor excreted by Vibrio parahaemolyticus, a marine bacterium that causes important losses in shrimp farming.
Francisco Javier Vazquez-Armenta, Uriel Felipe Valdez-Olmos, Aldo Alejandro Arvizu-Flores, Jesus Fernando Ayala-Zavala, Adrian Ochoa-Leyva, Alonso Alexis Lopez-Zavala   +5 more
doaj   +1 more source

Characterization of Plp, a phosphatidylcholine-specific phospholipase and hemolysin of Vibrio anguillarum [PDF]

, 2014
Background: Vibrio anguillarum is the causative agent of vibriosis in fish. Several extracellular proteins secreted by V. anguillarum have been shown to contribute to virulence.
Li, Ling, Mou, Xiangyu, Nelson, David R
core   +6 more sources

In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA). [PDF]

PLoS Pathogens, 2017
The O-acetylation of the essential cell wall polymer peptidoglycan occurs in most Gram-positive bacterial pathogens, including species of Staphylococcus, Streptococcus and Enterococcus. This modification to peptidoglycan protects these pathogens from the
David Sychantha, Carys S Jones, Dustin J Little, Patrick J Moynihan, Howard Robinson, Nicola F Galley, David I Roper, Christopher G Dowson, P Lynne Howell, Anthony J Clarke   +9 more
doaj   +1 more source

Proteome and immune responses of extracellular vesicles derived from macrophages infected with the periodontal pathogen Tannerella forsythia

Journal of Extracellular Vesicles, Volume 12, Issue 12, December 2023., 2023
Abstract Periodontitis is a chronic inflammatory disease caused by periodontal pathogens in subgingival plaque and is associated with systemic inflammatory diseases. Extracellular vesicles (EVs) released from host cells and pathogens carry a variety of biological molecules and are of interest for their role in disease progression and as diagnostic ...
Younggap Lim, Hyun Young Kim, Dohyun Han, Bong‐Kyu Choi   +3 more
wiley   +1 more source

Structural and Functional Characterisation of TesA - A Novel Lysophospholipase A from Pseudomonas aeruginosa [PDF]

, 2013
TesA from Pseudomonas aeruginosa belongs to the GDSL hydrolase family of serine esterases and lipases that possess a broad substrate- and regiospecificity.
Batra-Safferlin, Renu, Granzin, Joachim, Jaeger, Karl-Erich, Kojić-Prodić, Biserka, Kovačić, Filip, Wilhelm, Susanne   +5 more
core   +9 more sources

Flexure wood formation via growth reprogramming in hybrid aspen involves jasmonates and polyamines and transcriptional changes resembling tension wood development

New Phytologist, Volume 240, Issue 6, Page 2312-2334, December 2023., 2023
Summary Stem bending in trees induces flexure wood but its properties and development are poorly understood. Here, we investigated the effects of low‐intensity multidirectional stem flexing on growth and wood properties of hybrid aspen, and on its transcriptomic and hormonal responses.
János Urbancsok, Evgeniy N. Donev, Pramod Sivan, Elena van Zalen, Félix R. Barbut, Marta Derba‐Maceluch, Jan Šimura, Zakiya Yassin, Madhavi L. Gandla, Michal Karady, Karin Ljung, Sandra Winestrand, Leif J. Jönsson, Gerhard Scheepers, Nicolas Delhomme, Nathaniel R. Street, Ewa J. Mellerowicz   +16 more
wiley   +1 more source

Ruminococcal cellulosome systems from rumen to human [PDF]

, 2015
This article is protected by copyright. All rights reserved. The authors appreciate the kind assistance of Miriam Lerner (ImmunArray Ltd. Company, Rehovot, Israel) with experiments involving the MicroGrid II arrayer.
Bayer, Edward A, Bernalier-Donadille, Annick, Borovok, Ilya, Dassa, Bareket, David, Yonit Ben, Duncan, Sylvia H, Flint, Harry J, Koropatkin, Nicole M, Lamed, Raphael, Martens, Eric C, Moraïs, Sarah, White, Bryan A   +11 more
core   +3 more sources

Activity‐Based Protein Profiling in Methicillin‐Resistant Staphylococcus aureus Reveals the Broad Reactivity of a Carmofur‐Derived Probe

ChemBioChem, Volume 24, Issue 21, November 2, 2023., 2023
Enzyme targets of activity‐based probes built on the anti‐neoplastic drug and antimicrobial agent carmofur in methicillin‐resistant Staphylococcus aureus (MRSA) have been identified. Chemoproteomic profiling revealed a broad reactivity of the probe against both cysteine and serine hydrolases, and identified uncharacterized bacterial enzymes; this has ...
Md Jalal Uddin, Hermen S. Overkleeft, Christian S. Lentz   +2 more
wiley   +1 more source

A unique AA5 alcohol oxidase fused with a catalytically inactive CE3 domain from the bacterium Burkholderia pseudomallei

FEBS Letters, Volume 597, Issue 13, Page 1779-1791, July 2023., 2023
Copper radical oxidases (CROs) from Auxiliary Activities family 5 can oxidize various alcohol substrates. Bacterial CROs are less studied than eukaryotic enzymes. Here we have characterized an unusual bacterial CRO that acts only on primary alcohols and is fused to a carbohydrate esterase domain, which was completely inactive due to substitutions of ...
Scott Mazurkewich, Andrea Seveso, Johan Larsbrink   +2 more
wiley   +1 more source

Investigating the defoliating‐like (DL) VCG2A pathotype of Verticillium dahliae through identification and prediction of secreted proteins from genomes of Australian isolates

Plant Pathology, Volume 72, Issue 2, Page 334-341, February 2023., 2023
A defoliating‐like VCG2A Verticillium dahliae isolate was observed to have 20 secreted proteins in common with virulent phenotypes; interestingly half of these were most closely related to proteins from a VCG6 isolate. Abstract In Australia, recent investigations have reported the presence of a number of Verticillium dahliae pathotypes (VCG1A, VCG2A ...
John Webster, Pearl Dadd‐Daigle, Toni A. Chapman, Karen Kirkby   +3 more
wiley   +1 more source