Results 21 to 30 of about 726 (83)

Pengaruh Pemberian Ekstrak Daun Karika (Vasconcellea pubescens A.DC.) Terhadap Nilai SGPT dan SGOT pada Tikus Jantan yang Diinduksi Paracetamol

JPSCR: Journal of Pharmaceutical Science and Clinical Research, 2018
Parasetamol merupakan salah satu antipiretik yang sudah terbukti bisa menyebabkan kerusakan hati pada penggunaan dosis toksik. Kenaikan nilai SGPT (Serum Glutamat Piruvat Transaminase) dan SGOT (Serum Glutamat Oksaloasetat Transaminase) merupakan salah ...
Heru Sasongko, Sugiyarto Sugiyarto
doaj   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Fungsi Hati Anak Leukemia Limfoblastik Akut dalam Kemoterapi Fase Induksi berdasarkan Usia dan Status Gizi

Sari Pediatri
Latar belakang. Kemoterapi merupakan pengobatan utama pada anak leukemia limfoblastik akut (LLA). Kemoterapi fase induksi adalah kemoterapi pertama yang membunuh 95-98% sel leukemik.
Syahzalya Anggraini, Amirah Zatil Izzah, Fika Tri Anggraini, Yustini Alioes, Tuti Handayani   +4 more
doaj   +1 more source

Korelasi Kadar Plasminogen Activator Inhibitor-1 (PAI-1) Plasma dengan Enzim Transaminase Serum pada Demam Berdarah Dengue

Sari Pediatri, 2016
Latar belakang. Plasminogen activator inhibitor-1 (PAI-1) adalah inhibitor fibrinolisis yang berperan pada patogenesis demam berdarah dengue (DBD).
Budi Santosa, Kisdjamiatun RMD, Tatty Ermin, Ni Putu Aniek Mahayani   +3 more
doaj   +1 more source

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John, Nur Damia Iwani Zulkiflee, Siti Raihanah Shafie, Ramlah George, Melonney Patrick   +4 more
wiley   +1 more source

The Effect of Kerokan to Liver Function of Hepatitis B Patients

Global Medical & Health Communication, 2019
Kerokan is an alternative therapy done by rubbing and pressing the skin surface using oil and a blunt object. This treatment has a hepatoprotective effect as it increases heme oxygenase-1, an essential enzyme in heme catabolism.
Nur Adiba Hanum, Ismalayani Ismalayani, Rahmad Aswin Juliansyah, Syokumawena Syokumawena, Marta Pastari, Hanna Sari Widya Kusuma, Yukko Arinta   +6 more
doaj   +1 more source

Association of IFN‐γ +874 T/A Polymorphism With COVID‐19 Susceptibility, Severity, and Inflammatory Response: A Case–Control Study From Southern Iran

Journal of Clinical Laboratory Analysis, EarlyView.
Graphical abstract illustrating the association between IFN‐γ +874 T/A polymorphism and COVID‐19 outcomes. TA and AA genotypes are linked to increased susceptibility, higher inflammatory markers (notably IL‐6), greater disease severity, and longer hospitalization.
Nasir Arefinia, Bahman Aghcheli, Seyed Mohammad Ali Hashemi, Zohreh‐al‐sadat Ghoreshi, Emad Behboudi   +4 more
wiley   +1 more source

Perbandingan Perlindungan Minyak Jintan Hitam, Minyak Argan dan Minyak Zaitun terhadap Enzim Hati Tikus Akibat Diet Tinggi Lemak

Indonesian Journal of Pharmaceutical Education, 2023
High-fat diet has become one of the risk factors of liver dysfunction due to accumulation of fat in the liver cells. This disorder might be triggered by increased reactive oxygen species (ROS) activity with high-fat consumption.
Liska Alfaaizin, Aryadi Arsyad, Yulia Yusrini Djabir   +2 more
doaj   +1 more source

Reverse‐Engineered Lipid Nanoparticles Harness Protein Corona Formation for Cytokine Sequestration and Combination Immunomodulatory Therapy

Small, EarlyView.
Bioinspired triglyceride‐ceramide lipid nanoparticles were reverse‐engineered from cytokine‐sequestering plant‐derived nanoparticles to capture pathological inflammatory mediators through protein corona formation. Dexamethasone‐loaded TCNPs combine extracellular cytokine sequestration with intracellular immunomodulation, reducing IL‐6, TNF‐α, and NF‐κΒ
Junsik J. Sung, Gargi Yogesh Digholkar, Ryan M. Pearson   +2 more
wiley   +1 more source

Pengaruh Pemberian Ekstrak Etanol Keong Matah Merah (Cerithidea obstusa) Terhadap Kadar Enzim Transaminase Tikus Putih (Rattus novergicus)

Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan, 2022
Keong matah merah (Cerithidea obtusa) terbukti memiliki potensi farmakologis sebagai obat. Penelitian ini bertujuan menganalisis kadar enzim transaminase, yaitu serum glutamic pyruvic transaminase (SGPT) dan serum glutamic oxaloacetic transaminase (SGOT)
Dewi Ulfa Trisdiani, Sri Purwaningsih, Ekowati Handharyani   +2 more
doaj   +1 more source