Results 1 to 10 of about 13,567 (174)
Sappanwood extract modulates hepatic structure-function in hepatomegaly and hepcidin related iron regulatory pathways in a phenylhydrazine induced hemolytic anemia rat model relevant to thalassemia. [PDF]
Animal Model Exp MedPhenylhydrazine (PHZ) induces hemolytic anemia characterized by increased erythrocyte destruction and ineffective erythropoiesis, leading to hepcidin suppression through disruption of the BMP/SMAD signaling pathway. Reduced hepcidin levels enhance intestinal iron absorption and hepatic iron accumulation, leading to hepatic iron overload.
Pratama MI +5 more
europepmc +2 more sources
Ketosis Causing Spurious Elevation of SGOT Values
Clinical Chemistry, 1971 Abstract In two patients, spurious enhancements of SGOT on SMA 12/60 determination caused erroneous diagnoses of liver disease, which could have led to potentially hazardous diagnostic measures. Such errors can be avoided by an ultraviolet spectroscopic check of suspect SGOT values.
Paul L Wolf
exaly +3 more sources
Evaluation of The Use of Hydroxyurea in Treating Children With Sickle Cell Anemia in Central Africa's Rural Area. [PDF]
EJHaemABSTRACT Background Sickle cell anemia (SCA) is highly prevalent in Central Africa. This disease causes severe manifestations in children, requiring treatment. Hydroxyurea (HU) is currently the most effective treatment for SCA. We evaluated the use of HU in children living in rural Central Africa.
Mbayabo G +9 more
europepmc +2 more sources
Phenotypic profiling of pristane-induced mimicking human systemic lupus erythematosus in Macaca fascicularis. [PDF]
Animal Model Exp MedPristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny J +12 more
europepmc +2 more sources
Palm Oils Consumption Modulates Serum SGPT and SGOT in Rats Fed a High-Fat Diet [PDF]
BIO Web of Conferences, 2023 In this study we investigated the effect of three kinds of palm oil product (refined bleached deodorized palm oil (RBDPO), red palm oil (RPO) and palm kernel oil (PKO)) on the serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic ...
Utama Zaki +3 more
doaj +1 more source
Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan, 2022 Keong matah merah (Cerithidea obtusa) terbukti memiliki potensi farmakologis sebagai obat. Penelitian ini bertujuan menganalisis kadar enzim transaminase, yaitu serum glutamic pyruvic transaminase (SGPT) dan serum glutamic oxaloacetic transaminase (SGOT)
Dewi Ulfa Trisdiani +2 more
doaj +1 more source
Magna Medika, 2022 Background:Putri Malu plants (Mimosa pudica linn) contain flavonoid compounds that are useful as hepatoprotectors. Putri Malu plants extract can be usefull to prevent problem such as Ibuprofen-induced hepatic damage., but study that focus on this topic ...
Andre Bagaskara +5 more
doaj +1 more source
Indonesian Journal of Pharmaceutical Education, 2023 High-fat diet has become one of the risk factors of liver dysfunction due to accumulation of fat in the liver cells. This disorder might be triggered by increased reactive oxygen species (ROS) activity with high-fat consumption.
Liska Alfaaizin +2 more
doaj +1 more source