Results 31 to 40 of about 16,761 (170)

The Relationship between Duration of Benzene Exposure with Liver Enzymes in Car Painting Workshop Workers

The Indonesian Journal of Occupational Safety and Health, 2021
Introduction: Benzene is a carcinogenic compound that can be found in a car painting workshop in Surabaya. The source of benzene in the car painting workshop comes from thinners. Inhalation is the main route for benzene to enter the body. The duration of
Fitri Yatulaini, Abdul Rohim Tualeka, Juliana Jalaludin, Syamsiar S Russeng   +3 more
doaj   +1 more source

Hepatoprotective Activity of Ethanol Extract of Dewa Leaves (Gynura pseudochina (L.) DC) in White Rats (Rattus norvegicus) Induced by Paracetamol

Veterinary Biomedical and Clinical Journal
The use of paracetamol in excessive doses can increase the hepatotoxicity effect, which causes acute hepatocellular injury. Dewa leaves (Gynura pseudochina (L.) DC) contain flavonoids, saponin, and tannin.
Yelis Tria Monica, Shanti Listyawati, Elisa Herawati   +2 more
doaj   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Alterations in liver enzymes and histopathological changes in an animal model of polycystic ovary syndrome

Open Veterinary Journal
Background: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder that can lead to metabolic and reproductive complications, including liver dysfunction.
Yudit Oktanella, Muhammad Reza Fahlevi, Handayu Untari, Viski Fitri Hendrawan, Nabilla Rizky Mahalita, Jamilaturrosyidah Jamilaturrosyidah, Anna Lystia Poetranto   +6 more
doaj   +1 more source

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John, Nur Damia Iwani Zulkiflee, Siti Raihanah Shafie, Ramlah George, Melonney Patrick   +4 more
wiley   +1 more source

Amelioration of Cigarette Smoke-Induced Hepatic Injury by Green Tea (Camellia sinensis) Extract: Evidence from SGOT and SGPT Biomarkers in a Murine Model

Journal of Basic Medical Veterinary
This study investigated the hepatoprotective effects of green tea extract (GTE) against cigarette smoke-induced liver damage in mice. Twenty-five male mice (Mus musculus) were divided into five groups: negative control (C-), positive control exposed to ...
Putra Indrajaya, Mudawamah Mudawamah, Umi Kalsum, Adinda Rizky Trisakti, Aldin Akbar Rahmatullah   +4 more
doaj   +1 more source

Association of IFN‐γ +874 T/A Polymorphism With COVID‐19 Susceptibility, Severity, and Inflammatory Response: A Case–Control Study From Southern Iran

Journal of Clinical Laboratory Analysis, EarlyView.
Graphical abstract illustrating the association between IFN‐γ +874 T/A polymorphism and COVID‐19 outcomes. TA and AA genotypes are linked to increased susceptibility, higher inflammatory markers (notably IL‐6), greater disease severity, and longer hospitalization.
Nasir Arefinia, Bahman Aghcheli, Seyed Mohammad Ali Hashemi, Zohreh‐al‐sadat Ghoreshi, Emad Behboudi   +4 more
wiley   +1 more source

Analysis of serum glutamic pyruvic transaminase and serum glutamic oxaloacetic transaminase levels in tuberculosis patients who are undergoing oat treatment in Kendari City General Hospital, Kota Kendari, Indonesia

Infectious Disease Reports, 2020
In the treatment of tuberculosis (TB), the patient is generally directly given Anti Tuberculosis Drugs (Obat Anti Tuberculosis/OAT) without examining Serum Glutamic Pyruvic Transaminase (SGPT) and Serum Glutamic Oxaloacetic Transaminase (SGOT) to see ...
Sri Anggarini Rasyid, Armayani, Yuniati, Tiara Mayang Pratiwi Lio   +3 more
doaj   +1 more source

Reverse‐Engineered Lipid Nanoparticles Harness Protein Corona Formation for Cytokine Sequestration and Combination Immunomodulatory Therapy

Small, EarlyView.
Bioinspired triglyceride‐ceramide lipid nanoparticles were reverse‐engineered from cytokine‐sequestering plant‐derived nanoparticles to capture pathological inflammatory mediators through protein corona formation. Dexamethasone‐loaded TCNPs combine extracellular cytokine sequestration with intracellular immunomodulation, reducing IL‐6, TNF‐α, and NF‐κΒ
Junsik J. Sung, Gargi Yogesh Digholkar, Ryan M. Pearson   +2 more
wiley   +1 more source

Genetic and Clinical Determinants of Variation in Drug Response in Type 2 Diabetes: Insights From the Scottish and UK Biobank Cohorts

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Objective Treatment response in type 2 diabetes (T2D) varies widely among individuals. This study aimed to quantify the contributions of clinical characteristics and genetic predisposition as measured through partitioned polygenic risk scores (pPRS) to variation in glycemic response to glucose‐lowering therapies.
S. Garg, R. Kitchen, R. Gupta, L. Donnelly, E. R. Pearson   +4 more
wiley   +1 more source