Results 111 to 120 of about 46,179 (288)

Coupling Water Purification and Carbon Sequestration at Various Spatial Scales From Supply and Demand Perspective

Land Degradation &Development, EarlyView.
ABSTRACT Balancing ecosystem‐service supply and demand is central to understanding both the natural and social dimensions of ecosystem services and to enhancing human well‐beings. Concurrently, collaborative efforts are underway to improve multiple ecosystem services, including the promotion of carbon neutrality and water purification (WP) within basin
Jing Cheng, Mingyang Ding, Zhenya Zhu, Xinping Luo, Xin Huang, Chunbo Huang   +5 more
wiley   +1 more source

Perampanel Blocks Transsynaptic α‐Synuclein Propagation and Neurodegeneration in a Mouse Model of Lewy Body Disease

Movement Disorders, EarlyView.
Abstract Background Transsynaptic α‐synuclein propagation plays a crucial role in the progression of Lewy body disease. We previously demonstrated that an α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor antagonist, perampanel, blocks neuronal uptake of α‐synuclein preformed fibrils (PFFs) in an activity‐dependent manner.
Jun Ueda, Norihito Uemura, Jiarui Chang, Tetsuya Hirato, Tomoyuki Ishimoto, Miki Oono, Shuichi Matsuzawa, Riki Matsumoto, Hodaka Yamakado, Ryosuke Takahashi   +9 more
wiley   +1 more source

Investigating the Sensitivity of the Diffusion MRI Signal to Magnetization Transfer and Permeability via Monte‐Carlo Simulations

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Magnetization transfer (MT) and water exchange via permeability operate on a similar spatiotemporal scale to water diffusion. In this study, we use a simulation‐based approach to characterize how MT and permeability impact (1) diffusion‐weighted MRI (dMRI) measurements from cylindrical substrates and (2) parameter estimation using a ...
Zhiyu Zheng, Karla L. Miller, Benjamin C. Tendler, Michiel Cottaar   +3 more
wiley   +1 more source

GABA+‐Edited Magnetic Resonance Spectroscopy Deep Learning Quality Assessment Framework

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Motivated by the need to improve GABA+‐edited magnetic resonance spectroscopy (MRS) quality, we developed a three‐module framework to improve transient averaging based on quality. We hypothesized that training a deep learning (DL) model to differentiate spectrum quality could improve transient averaging compared to traditional ...
Hanna Bugler, Roberto Souza, Ashley D. Harris   +2 more
wiley   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Inverse Shifting-PCR Modified by Capillary Electrophoresis for Detecting F8 int22h and int1h Inversions in Severe Hemophilia A Patients and Probable Carriers

Life
Globally, intron 22 inversions (Inv22s) of the factor VIII gene (F8) are the most frequent pathogenic variants and account for 45–50% of severe hemophilia A (SHA) cases, while intron 1 inversion (Inv1) explains 1–5% of SHA cases.
Rosa Michel Martínez-Contreras, Silvia Sofía García-López, Hilda Luna-Záizar, Ana Rebeca Jaloma-Cruz   +3 more
doaj   +1 more source

Parallelizing SHA-1

IEICE Electronics Express, 2015
Hu-ung Lee, Seongjing Lee, Jae-woon Kim, Youjip Won   +3 more
openaire   +2 more sources

Susceptibility of Phthorimaea absoluta (Meyrick) (Lepidoptera: Gelechiidae) to novel and established insecticides in Brazil: resistance survey, baseline, and implications for management

Pest Management Science, EarlyView.
Baseline susceptibility of Phthorimaea absoluta to novel insecticides isocycloseram and tolfenpyrad was established in Brazil. Diagnostic doses were proposed for early resistance detection. Early tolfenpyrad tolerance and abamectin‐driven cross‐tolerance to isocycloseram via oxidases highlight cross‐resistance risks, emphasizing the need for routine ...
Vitor Quintela, Teófilo P Langa, José VCR Dantas, Marcos de Oliveira, Herbert AA Siqueira   +4 more
wiley   +1 more source

Measure to manage – an integrated pest management metric for horticulture

Pest Management Science, EarlyView.
IPM metric for food horticulture applied to growers in four countries. Overall average score = 58/100. Top fruit growers averaged highest (M = 61). Growers from England scored highest overall & indicated strong adoption of core components Policy is an influencing factor, evidenced by adoption rates in England Policy must function at farm level to ...
Jennifer Byrne, Robert Lillywhite, Fiona Thorne, Lael Walsh, Henry Creissen   +4 more
wiley   +1 more source

Spatiotemporal Assessment of Groundwater Interactions With a Regulated River: A Case Study of the Nechako River, Canada

River Research and Applications, EarlyView.
ABSTRACT Regulated rivers represent complex hydrological systems where groundwater–surface water interactions are governed by natural conditions and human interventions. This study investigates the spatiotemporal dynamics of groundwater–surface water exchanges in the Nechako River, British Columbia (Canada), using numerical simulations.
Milad Fakhari, John Gray, Avery Dextrase, Andre St‐Hilaire, Richard Martel   +4 more
wiley   +1 more source