Results 141 to 150 of about 46,179 (288)

A systematic review of generative AI in education: Empirical insights from a human–AI interaction perspective

open access: yesBritish Journal of Educational Technology, EarlyView.
Abstract With the increasing application of GenAI in education, researchers and practitioners are paying more and more attention to its effectiveness and impact in teaching and learning. This can be evidenced by the increasing number of literature reviews on this topic published in recent years.
Zhiping Liang   +5 more
wiley   +1 more source

Palaeowinds and depositional conditions from Holocene loess in Sweden and Finland

open access: yesBoreas, EarlyView.
The nature of deglacial and Holocene wind regimes in Fennoscandia is debated, as is the degree to which wind‐blown loess deposits exist in the region. Loess deposits in Fennoscandia are often relatively thin, discontinuous and less well‐sorted than typical loess, and questions remain over the degree of their post‐depositional reworking and the impact ...
Calum J. Edward   +6 more
wiley   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

open access: yesBrain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga   +11 more
wiley   +1 more source

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

open access: yesBrain Pathology, EarlyView.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña   +20 more
wiley   +1 more source

Effectiveness and Predictors of House Dust Mite Subcutaneous Immunotherapy in Polysensitised Patients With Allergic Rhinitis: A Multicentre Retrospective Study

open access: yesClinical &Experimental Allergy, EarlyView.
Single‐allergen dust mite subcutaneous immunotherapy achieved 68.8% perennial symptom response rate in polysensitised allergic rhinitis patients. High mould and dust mite sIgE levels predicted poor allergen immunotherapy response, which indicated allergen‐specific sIgE levels may help guide personalised allergen immunotherapy decisions.
Zhouxian Pan   +13 more
wiley   +1 more source

Controllable Intrinsic Surface Pattern Generation Using Slime Mold Simulations

open access: yesComputer Graphics Forum, EarlyView.
Abstract Surface‐based pattern simulations have proven valuable for texture design and scientific visualization, but existing methods face several limitations. Most simulations either target a narrow range of pattern types (e.g. spots, branching) or support a broad range of patterns at the cost of time‐consuming parameter tuning.
Jeffrey Layton   +2 more
wiley   +1 more source

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