Results 91 to 100 of about 1,019,635 (350)

The shadow economy of Armenia: size, causes and consequences [PDF]

, 2005
Over the past decade or so the problems caused by the shadow economy have become a major concern for policy makers, researchers, as well as the donor community in Armenia.
Tunyan, Bagrat
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Pixel-wise Orthogonal Decomposition for Color Illumination Invariant and Shadow-free Image

, 2015
In this paper, we propose a novel, effective and fast method to obtain a color illumination invariant and shadow-free image from a single outdoor image.
Han, Zhi, Qu, Liangqiong, Tang, Yandong, Tian, Jiandong   +3 more
core   +1 more source

Shadowing for Pronunciation Development : Haptic-Shadowing and IPA-Shadowing [PDF]

The Journal of AsiaTEFL, 2018
Shadowing was introduced to foreign language teaching in the 1990s and since then it has been researched in EFL teaching contexts. Shadowing has been used as a listening task, and its effectiveness on listening comprehension has been acknowledged. However, its effect on pronunciation development remains unclear.
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Shadow Sorting [PDF]

This paper investigates the border between formal employment, shadow employment, and unemployment in an equilibrium model of the labor market with market frictions.
Pietro Garibaldi, Tito Boeri
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Probe of the Solar Magnetic Field Using the "Cosmic-Ray Shadow" of the Sun

, 2013
We report on a clear solar-cycle variation of the Sun's shadow in the 10 TeV cosmic-ray flux observed by the Tibet air shower array during a full solar cycle from 1996 to 2009.
Amenomori, M., Bi, X. J., Chen, D., Chen, T. L., Chen, W. Y., Cui, S. W., Danzengluobu, Ding, L. K., Feng, C. F., Feng, Z. Y., Feng, Zhaoyang, Gou, Q. B., Guo, Y. Q., Hakamada, K., He, H. H., He, Z. T., Hibino, K., Hotta, N., Hu, H. B., Hu, Haibing, Huang, J., Jia, H. Y., Jiang, L., Kajino, F., Kasahara, K., Katayose, Y., Kato, C., Kawata, K., Labaciren, Le, G. M., Li, A. F., Li, H. J., Li, W. J., Liu, C., Liu, J. S., Liu, M. Y., Lu, H., Meng, X. R., Mizutani, K., Munakata, K., Nanjo, H., Nishizawa, M., Ohnishi, M., Ohta, I., Onuma, H., Ozawa, S., Qian, X. L., Qu, X. B., Saito, T., Saito, T. Y., Sakata, M., Sako, T. K., Shao, J., Shibata, M., Shiomi, A., Shirai, T., Sugimoto, H., Takita, M., Tan, Y. H., Tateyama, N., Torii, S., Tsuchiya, H., Udo, S., Wang, H., Wu, H. R., Xue, L., Yamamoto, Y., Yang, Z., Yasue, S., Yuan, A. F., Yuda, T., Zhai, L. M., Zhang, H. M., Zhang, J. L., Zhang, X. Y., Zhang, Y., Zhang, Yi, Zhang, Ying, Zhaxisangzhu, Zhou, X. X.   +79 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source