Results 101 to 110 of about 931,571 (297)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Flux imbalance analysis and the sensitivity of cellular growth to changes in metabolite pools [PDF]
, 2013 Stoichiometric models of metabolism, such as flux balance analysis (FBA), are classically applied to predicting steady state rates - or fluxes - of metabolic reactions in genome-scale metabolic networks. Here we revisit the central assumption of FBA, i.e.
Mehta, Pankaj +2 more
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Jungian Archetypes and the Confluence of Anima and Animus in Heart of Darkness
University of Chitral Journal of Linguistics and Literature, 2022 This paper discusses Carl Jung’s theory of individuation by exploring the archetypes of anima and animus as portrayed in Conrad’s Heart of Darkness.
Muhammad Yousaf Khan +1 more
doaj
How do Institutions Affect Corruption and the Shadow Economy? [PDF]
This paper analyzes a simple model that captures the relationship between institutional quality, the shadow economy and corruption. It shows that an improvement in institutional quality reduces the shadow economy and affects the corruption market.
Axel Dreher +2 more
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Remote Sensing, 2018 An alternative technique for shadow detection and abundance is presented for high spatial resolution imagery acquired under clear sky conditions from airborne/spaceborne sensors.
Mark Cameron, Lalit Kumar
doaj +1 more source
Shadow Economies around the World: What do we really know? [PDF]
Using the DYMIMIC approach, estimates of the shadow economy in 110 developing, transition and developed OECD countries are presented. The average size of the shadow economy (in percent of official GDP) over 1999-2000 in developing countries is 41%, in ...
Friedrich Schneider
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Remote Sensing, 2019 To improve the accuracy of analysis outputs from remotely sensed images, shadow and illumination effects need to be minimised or removed. Shadow behaviour at different spectral wavelengths needs to be understood to quantify shadow accurately.
Mark Cameron, Lalit Kumar
doaj +1 more source