Results 131 to 140 of about 33,305 (299)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
A Review on Various Shadow Detection and Compensation Techniques in Remote Sensing Images
Canadian Journal of Remote Sensing, 2017 Remote sensing images provide a valuable source of information about the earth's surface. The presence of shadow can reduce the amount of information that can be extracted from these images.
Yasser Mostafa
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Moving Target Shadow Detection Method Based on Improved ViBe in VideoSAR Images
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingThe video synthetic aperture radar (VideoSAR) has the high frame-rate imaging capability, which can perform the ground moving target detection. The moving target often leaves the shadow in the sequence of the VideoSAR images, which can indirectly detect ...
Zhitao Wu +4 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Document Image Shadow Removal Based on Illumination Correction Method
AlgorithmsDue to diverse lighting conditions and photo environments, shadows are almost ubiquitous in images, especially document images captured with mobile devices.
Depeng Gao +5 more
doaj +1 more source
Local Water-Filling Algorithm for Shadow Detection and Removal of Document Images. [PDF]
Sensors (Basel), 2020 Wang B, Chen CLP.
europepmc +1 more source
Measuring the Shadow Economy with the Currency Demand Approach - A Reinterpretation of the methodology, with an application to Italy [PDF]
We contribute to the debate on how to assess the size of the shadow economy by proposing a reinterpretation of the traditional Currency Demand Approach (CDA) a là Tanzi. In particular, we introduce three main innovations.
Guerino Ardizzi +3 more
core