β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source
Clinical AI Beyond Development: A Scoping Review of Deployment-Related Robustness, Algorithmovigilance, and Lifecycle Oversight. [PDF]
El Arab RA +7 more
europepmc +1 more source
Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios +5 more
wiley +1 more source
Re-emerging Marburg virus disease in Africa: spillover ecology, geographic expansion, and surveillance vulnerabilities. [PDF]
Tibbo M, Barigye R, Ameni G.
europepmc +1 more source
A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed +6 more
wiley +1 more source
From Microscale to Nanoscale Shadow Electrochemiluminescence Microscopy. [PDF]
Gou X +5 more
europepmc +1 more source
Purple Potato and Its Polyphenols Modulate Cecal Fermentation in Rats. [PDF]
Chiba M +6 more
europepmc +1 more source
Application of ultrasound biomicroscopy in ocular trauma caused by chestnut-burr spines. [PDF]
Zhou M, Sun X, Wu J, Kong Q, Su Y, Li D.
europepmc +1 more source
Health Risk Assessment of Cadmium in Brazilian Makeup Products Using a Novel MDSPE-FAAS Method. [PDF]
de Souza MS +8 more
europepmc +1 more source

