Results 91 to 100 of about 1,214,646 (321)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
THE CONCEPTUAL ROLE OF THE SHADOW ECONOMY IN ECONOMIC GROWTH
Економіка та суспільствоThe article examines the conceptual role of the shadow and gray economies in economic growth and substantiates the need to take them into account in multifactor models of economic development.
Юрій Коляда +1 more
doaj +1 more source
This paper investigates the border between formal employment, shadow employment, and unemployment in an equilibrium model of the labor market with market frictions.
Pietro Garibaldi, Tito Boeri
core
Shadow writing and participant observation : a study of criminal justice social work around sentencing [PDF]
, 2008 The study of decision-making by public officials in administrative settings has been a mainstay of law and society scholarship for decades. The methodological challenges posed by this research agenda are well understood: how can socio-legal researchers ...
Burns, Nicola +4 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
State Management of the Employment in the Conditions of the Economic Crisis
Управленческое консультирование, 2019 The article considers the current problems of the employment state management. The characteristic of the role of employment management in the system of state economic regulation is given.
M. Yu. Elsukov, R. R. Amirov
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
UNDECLARED WORK IN POLAND CHARACTERISTICS AND PREVALENCE
Ekonomika, 2016 This article aims to present the significance and prevalence of the phenomenon of undeclared work. First, we discuss the definitional issues of this phenomenon. Then, we present previous estimates on shadow economy and undeclared work in Poland, based on
Dagmara Nikulin
doaj +1 more source
Shadow Economies in highly developed OECD countries: What are the driving forces? [PDF]
, 2013 The main focus of this paper lies on the driving forces of the development and size of the shadow economy in 39 highly developed OECD countries. The most influential factors on the shadow economy are tax policies and state regulation, which, if rising ...
Buehn, Andreas, Schneider, Friedrich
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source